8 products were found matching "AG-40A-0065-C050"!

Recognizes human FGF-19. Detects a band of about 25kDa by Western blot. Liquid. 0.2µm-filtered solution in PBS, pH 7.4. Contains no preservatives. FGF-19 is involved in the suppression of bile acid biosynthesis through down-regulation of CYP7A1 expression, following positive regulation of the JNK and ERK1/2...

Human FGF-21 (amino acids 1-209) is fused at the C-terminus to the Fc portion of human IgG1. Activates ERK and FRS2alpha phosphorylation in bKlotho expressing cells. Liquid. 0.2µm-filtered solution in PBS. FGF-21 (Fibroblast growth factor 21) stimulates glucose uptake in differentiated adipocytes via the induction...

Mouse ANGPTL4 (amino acids 1-410) is fused at the C-terminus to a FLAG(R)-tag. Activates ERK phosphorylation in THP-1 cells. Liquid. 0.2µm-filtered solution in PBS. ANGPTL4 (Angiopoietin-like protein 4) mainly expressed in endothelial cells (hypoxia-induced). Regulates angiogenesis and modulates tumorigenesis and...

Human ANGPTL7 (amino acids 1-346) is fused at the C-terminus to a FLAG(R)-tag. Activates ERK phosphorylation in THP-1 cells. Liquid. 0.2µm-filtered solution in PBS. ANGPTL7 (Angiopoietin-like protein 7) is expressed in various tissues and regulates angiogenesis. Human ANGPTL7 was characterized as a potent target...

Human FABP4 (amino acids 1-132) is fused at the C-terminus to a His-tag. Liquid. 0.2µm-filtered solution in 55mM TRIS-Cl, pH 8.2, containing 200mM NaCl. FABP4 is a fatty acid binding protein in adipocytes. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain...

The extracellular domain of mouse CD137 (amino acids 1-185) is fused at the C-terminus to the Fc portion of human IgG1. Liquid. 0.2µm filtered solution in PBS. CD137 (4-1BB) is a member of the tumor necrosis factor (TNF) receptor family. CD137 is expressed by activated T cells, dendritic cells, NK cells,...

Mouse RBP4 (amino acids 19-201) is fused at the N-terminus to a FLAG(R)-tag. Liquid. 0.2µm-filtered solution in PBS, pH 7.2. Retinol binding protein 4 (RBP4, RBP) is a 21kDa secreted protein, a member of the lipocalin family and is known as the primary transporter of retinol (vitamin A) to tissues. A recent report...

Signal peptide and human progranulin (aa 1-593) are fused at the C-terminus to a FLAG(R)-tag. Activates ERK phosphorylation in THP-1 and MCF10A cells and induces cell migration of THP-1 monocytic leukemia cells. Progranulin (PGRN) is a widely expressed pluripotent growth factor which plays a role in processes such...