8 products were found matching "AG-40A-0096-C010"!

IL-36Ralpha/IL-1F5 is a highly and a specific antagonist of the IL-1 receptor-related protein 2-mediated response to IL-36alpha (IL-1F6), IL-36beta (IL-1F8) and IL-36gamma (IL-1F9). These cytokines bind to IL-36R (IL-1Rrp2) and IL-1RAcP, activating similar intracellular signals as IL-1. IL-36Ralpha inhibits the...

Human FGF-21 (amino acids 1-209) is fused at the C-terminus to the Fc portion of human IgG1. Activates ERK and FRS2alpha phosphorylation in bKlotho expressing cells. Liquid. 0.2µm-filtered solution in PBS. FGF-21 (Fibroblast growth factor 21) stimulates glucose uptake in differentiated adipocytes via the induction...

Mouse FGF-21 (amino acids 1-210) is fused at the C-terminus to the Fc portion of human IgG. Liquid. 0.2µm-filtered solution in PBS. FGF-21 (Fibroblast growth factor 21) stimulates glucose uptake in differentiated adipocytes via the induction of glucose transporter SLC2A1/GLUT1 expression (but not SLC2A4/GLUT4...

Progranulin (PGRN) is a widely expressed pluripotent growth factor which plays a role in processes such as development, wound repair and inflammation by activating signaling cascades that control cell cycle progression and cell motility. Its function in the central nervous system is of interest, as mutations in the...

SIGIRR acts as a negative regulator of the Toll-like and IL-1R receptor signaling pathways. Attenuates the recruitment of receptor-proximal signaling components to the TLR4 receptor, probably through a TIR-TIR domain interaction with TLR4. Protein function: Acts as a negative regulator of the Toll-like and IL-1R...

Protein function: Stimulates glucose uptake in differentiated adipocytes via the induction of glucose transporter SLC2A1/GLUT1 expression (but not SLC2A4/GLUT4 expression). Activity requires the presence of KLB. [The UniProt Consortium] The fibroblast growth factor (FGF) family is a group of multifunctional...

Recombinant protein. Mouse vaspin (aa 21-413) is fused at the N-terminus to a FLAG(R)-tag. Produced in HEK 293 cells. Endotoxin: 95% (SDS-PAGE). Vaspin (Visceral adipose tissue-derived serpin, Serpin A12), a serine protease inhibitor (serpin), is an insulin-sensitizing adipocytokine that has been isolated from both...

Nicotinamide phosphoribosyltransferase (Nampt, pre-B cell colony-enhancing factor, PBEF, Visfatin) is an adipokine that is localized to the bloodstream and has various functions, including the promotion of vascular smooth muscle cell maturation and inhibition of neutrophil apoptosis. It activates insulin receptor...