- Search results for Cay13965
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9 products were found matching "Cay13965"!
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Item number: Cay13965-5
AMI-1 is a cell permeable inhibitor of PRMTs. It inhibits both yeast Type I arginine methyltransferase Hmt1p and human PRMT1 (IC50 = 3.0 and 8.8 µM, respectively). AMI-1 also effectively blocks the activity of PRMTs 3, 4, and 6 but not that of either SET (Sub39H1, Suv39H2, SET7) or non-SET (DOT1) lysine...
Keywords: | Arginine N-Methyltransferase Inhibitor-1, 7,7'-(carbonylbis(azanediyl))bis(4-oxidonaphthalene-2-sulfonate), sodium salt |
Application: | PRMTs Inhibitor |
MW: | 592.4 D |
From 125.00€
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Item number: Cay13966-5
EPZ005687 is a potent, selective inhibitor of the lysine methyltranferase EZH2 (Ki = 24 nM), the enzymatic subunit of polycomb repressive complex 2 (PRC2). It acts competitively with the EZH2 substrate S-adenosylmethionine. EPZ005687 has greater than 500-fold selectivity against 15 other protein methyltransferases...
Keywords: | 1-cyclopentyl-N-[(1,2-dihydro-4,6-dimethyl-2-oxo-3-pyridinyl)methyl]-6-[4-(4-morpholinylmethyl)phenyl]-1H-indazole-4-carbo... |
Application: | Lysine methyltranferase EZH2 inhibitor |
CAS | 1396772-26-1 |
MW: | 539.7 D |
From 115.00€
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Item number: Cay13996-5
MDL 72527 is a polyamine oxidase (PAO) inhibitor that inhibits spermine oxidase and N1-acetylpolyamine oxidase (IC50s = 6.1 and 0.02 µM, respectively). It does not inhibit monoamine oxidase or D-amino acid oxidase. MDL 72527 inhibits PAO-dependent H2O2 production in vitro and in vivo and is used to study the role of...
Keywords: | N1,N4-di-2,3-butadien-1-yl-1,4-butanediamine, dihydrochloride |
Application: | PAO inhibitor |
CAS | 93565-01-6 |
MW: | 265.2 D |
From 50.00€
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Item number: Cay13961-5
6-NBDG is a non-hydrolyzable fluorescent glucose analog that is used to monitor glucose uptake and transport in living cells. 6-NBDG has been validated as a probe for the glucose transporter GLUT1 in cells. The fluorophore NBD displays excitation/emission maxima of 465/535 nm.Formal Name:...
Keywords: | 6-NBD-Glucose, 6-deoxy-6-[(7-nitro-2,1,3-benzoxadiazol-4-yl)amino]-D-glucose |
Application: | Glucose uptake / transport monitoring, nonhydrolyzable fluorescent glucose analog |
CAS | 108708-22-1 |
MW: | 342.3 D |
From 104.00€
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Item number: Cay13967-5
DOT1L is a protein methyltransferase (PMT). It is the only enzyme known to methylate histone 3 at lysine 79 (H3K79), where it catalyzes mono-, di-, and trimethylation. Proper DOT1L function is necessary for transcriptional activation of many genes, DNA damage repair, and cell cycle regulation. SGC0946 is a potent...
Keywords: | 5-bromo-7-[5-deoxy-5-[[3-[[[[4-(1,1-dimethylethyl)phenyl]amino]carbonyl]amino]propyl](1-methylethyl)amino]-beta-D-ribofura... |
Application: | Potent DOT1L inhibitor |
CAS | 1561178-17-3 |
MW: | 618.6 D |
From 129.00€
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Item number: Cay13969-5
3,4-Methylenedioxyamphetamine (MDA) is psychedelic and entactogenic drug that is scheduled as a controlled substance in the United States. 2,3-MDA is a structural isomer of MDA which differs only in the placement of the methyledioxy group. The physiological and toxicological properties of this compound are not...
Keywords: | 2,3-Methylenedioxyamphetamine, alpha-methyl-1,3-Benzodioxole-4-ethanamine, monohydrochloride |
Application: | Analytical reference standard, MDA structural homolog |
CAS | 86029-48-3 |
MW: | 215.7 D |
From 241.00€
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Item number: Cay13963-5
3C-B-FLY is an alpha-methylated analog of 2C-B-FLY. This compound is also the dihydrofuran analog of 4-bromo-2,5-dimethoxyamphetamine (Cay-11142), which is a potent agonist of 5-HT2A and 5-HT2C. The physiological and toxicological properties of 3C-B-FLY are not known. This product is intended for forensic and...
Keywords: | 8-bromo-2,3,6,7-tetrahydro-alpha-methyl-benzo[1,2-b:4,5-b']difuran-4-ethanamine, monohydrochloride |
Application: | Analytical reference standard, 2C-B-FLY alpha-methylated analog |
CAS | 178557-19-2 |
MW: | 334.6 D |
From 109.00€
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Item number: Cay13968-5
Methyllysine (Kme) recognition "reader" domains play a central role in epigenetic regulation during cellular differentiation, development, and gene transcription. UNC1215 is a potent and selective chemical probe for the Kme reading function of L3MBTL3, a member of the malignant brain tumor (MBT) family of chromatin...
Keywords: | (2-(phenylamino)-1,4-phenylene)bis((4-(pyrrolidin-1-yl)piperidin-1-yl)methanone) |
Application: | L3MBTL3 probe |
CAS | 1415800-43-9 |
MW: | 529.7 D |
From 65.00€
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Item number: Cay13964-5
LY333531 is an inhibitor of PKCbeta (IC50s = 4.7 and 5.9 nM for PKCbeta1 and PKCbeta2, respectively). It is selective for PKCbeta1 and PKCbeta2 over PKCalpha, -gamma, -delta, -epsilon, -zeta, and -eta (IC50s = 360, 300, 250, >100,000, and 52 nM, respectively). LY333531 also inhibits glycogen synthase kinase 3beta...
Keywords: | Ruboxistaurin,... |
Application: | PKCbeta1/PKCbeta2 Inhibitor |
CAS | 169939-93-9 |
MW: | 505 D |
From 142.00€
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