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Letrozole
Item number: Cay11568-25
Letrozole is a potent, cell-permeable inhibitor of aromatase (IC50 = 2 nM). It inhibits proliferation of estrogen receptor-positive (ER+) MCF-7 cells when used alone at concentrations ranging from 0.1 to 100 nM and when used at a concentration of 10 nM in combination with testosterone or 4-androstene-3,17-dione. It...
| Keywords: | CGS 20267, 4,4'-(1H-1,2,4-triazol-1-ylmethylene)bis-benzonitrile |
| Application: | Aromatase inhibitor, chemoprevention |
| CAS | 112809-51-5 |
| MW: | 285.3 D |
From 60.00€
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Dexmedetomidine (hydrochloride)
Item number: Cay15581-10
Dexmedetomidine is the (S)-enantiomer of medetomidine, an imidazole compound that binds to alpha2-adrenoceptors (Ki = 1.08 nM) with high affinity and selectivity compared to that of alpha1-adrenoceptors (Ki = 1.8 µM). Dexmedetomidine produces analgesic, sedative, and anxiolytic effects through both presynaptic...
| Keywords: | Dex, Precedex, 5-[(1S)-1-(2,3-dimethylphenyl)ethyl]-1H-imidazole, monohydrochloride |
| Application: | alpha2-adrenergic receptor agonist |
| CAS | 145108-58-3 |
| MW: | 236.7 D |
From 66.00€
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