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Item number: LKT-A0777.5

ABT-263 is a BH3 mimetic that inhibits Bcl-2 and Bcl-xl. ABT-263's inhibition of Bcl-xl results in thrombocytopenia, limiting its usage. ABT-263 exhibits anticancer chemotherapeutic activity and shows some benefit in clinical trials. In chronic lymphocytic leukemia (CLL) cells, ABT-263 inhibits cell proliferation....

Keywords:	Navitoclax, A-855071
Application:	BH3 mimetic, Bcl-2 / Bcl-xl inhibitor
CAS	923564-51-6
MW:	974.61 D

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