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ABT-199
ABT-199

Item number: LKT-A0776.5

ABT-199 is a BH3 mimetic that inhibits Bcl-2 but does not affect Bcl-xl. ABT-199 exhibits anticancer chemotherapeutic activity, inducing Bim-mediated apoptosis in chronic lymphocytic leukemia (CLL) cells. ABT-199 also induces cell death and inhibits tumor growth in acute myelogenous leukemia (AML) models in vitro,...
Keywords: GDC-0199
Application: BH3 mimetic, Bcl-2 inhibitor
CAS 1257044-40-8
MW: 868.44 D
From 69.00€ *
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