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Kanosamine (hydrochloride)
Kanosamine (hydrochloride)

Item number: Cay16623-5

Kanosamine, a constituent of kanamycin, is an antibiotic produced by Streptomyces and Bacillus that can inhibit cell wall synthesis in plant-pathogenic oomycetes (MIC = 25 µg/ml for P. medicaginis M2913) and certain fungi as well as some bacterial species (MIC = 400 µg/ml for S. aureus). It has been explored as an...
Keywords: 3-amino-3-deoxy-D-glucose, monohydrochloride
Application: Antibiotic
CAS 57649-10-2
MW: 215.6 D
From 60.00€ *
Review
AWD 131-138
AWD 131-138

Item number: Cay16235-10

AWD 131-138 is a partial agonist of the GABAA receptor that acts at the benzodiazepine binding site, dose-dependently stimulating GABA currents with a threshold of 0.3-1.0 µM. This effect is blocked by the benzodiazepine antagonist flumazenil (Cay-14252). AWD 131-138 displays a broad spectrum of anticonvulsant...
Keywords: ELB138, Imepitoin, 1-(4-chlorophenyl)-1,5-dihydro-4-(4-morpholinyl)-2H-imidazol-2-one
Application: Partial benzodiazepine receptor agonist
CAS 188116-07-6
MW: 279.7 D
From 142.00€ *
Review
ABT-199
ABT-199

Item number: Cay16233-25

B-cell lymphoma/leukemia 2 (Bcl-2) is an anti-apoptotic protein that controls cell survival by binding the BH3 domains of pro-death BAD and BAK proteins and preventing permeabilization of the mitochondrial outer membrane. This protein is tightly regulated for the homeostasis between cell growth and cell death. The...
Keywords: Venetoclax, GDC 0199,...
Application: BCL-2 inhibitor
CAS 1257044-40-8
MW: 868.4 D
From 72.00€ *
Review