ABIN-1, Recombinant, Human (TNIP1, TNFAIP3 Interacting Protein 1, HIV-1 Nef-interacting Protein, Nef

ABIN-1, Recombinant, Human (TNIP1, TNFAIP3 Interacting Protein 1, HIV-1 Nef-interacting Protein, Nef
Item number Size Datasheet Manual SDS Delivery time Quantity Price
A0004-74H.10 10 µg - -

3 - 19 business days*

568.00€
 
TNIP1 (TNFAIP3-interacting protein 1) has been shown to interacts with zinc finger protein... more
Product information "ABIN-1, Recombinant, Human (TNIP1, TNFAIP3 Interacting Protein 1, HIV-1 Nef-interacting Protein, Nef"
TNIP1 (TNFAIP3-interacting protein 1) has been shown to interacts with zinc finger protein A20/TNFAIP3 and inhibits TNF-induced NF-kappa-B-dependent gene expression by interfering with an RIP- or TRAF2-mediated transactivation signal. In addition, interacts with HIV-1 matrix protein and is packaged into virions and overexpression can inhibit viral replication. It may regulate matrix nuclear localization, both nuclear import of PIC (Preintegration complex) and export of GAG polyprotein and viral genomic RNA during virion production. Source: Recombinant corresponding to aa94-530 of human TNIP1 protein, fused to His-tag at N-terminus, expressed in E.coli. AA Sequence: MGSSHHHHHH SSGLVPRGSH MSNVTASPTA PACPSDKPAP VQKPPSSGTS SEFEVVTPEE QNSPESSSHA NAMALGPLPR EDGNLMLHLQ RLETTLSVCA EEPDHGQLFT HLGRMALEFN RLASKVHKNE QRTSILQTLC EQLRKENEAL KAKLDKGLEQ RDQAAERLRE ENLELKKLLM SNGNKEGASG RPGSPKMEGT GKKAVAGQQQ ASVTAGKVPE VVALGAAEKK VKMLEQQRSE LLEVNKQWDQ HFRSMKQQYE QKITELRQKL ADLQKQVTDL EAEREQKQRD FDRKLLLAKS KIEMEETDKE QLTAEAKELR QKVKYLQDQL SPLTRQREYQ EKEIQRLNKA LEEALSIQTP PSSPPTAFGS PEGAGALLRK QELVTQNELL KQQVKIFEED FQRERSDRER MNEEKEELKK QVEKLQAQVT LSNAQLKAFK DEEKAREALR QQKRKAKA, Molecular Weight: 51.8kD (458aa) confirmed by MALDI-TOF , Storage and Stability:, May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Keywords: VAN, Naf1, hVAN, TNIP1, ABIN-1, Nip40-1, KIAA0113, Nef-associated factor 1, HIV-1 Nef-interacting protein, TNFAIP3-interacting protein 1, Virion-associated nuclear shuttling protein, A20-binding inhibitor of NF-kappa-B activation 1
Supplier: United States Biological
Supplier-Nr: A0004-74H

Properties

Conjugate: No
Species reactivity: human
Format: Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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