10 products were found matching "Cay36360"!

8(S)-HETrE is a metabolite of the omega-6 fatty acid gamma-linolenic acid (GLA, Cay-90220). It is formed from GLA by 5-lipoxygenase (5-LO) via a dihomo-gamma-linolenic acid (Cay-90230) intermediate. Serum levels of 8(S)-HETrE are decreased in a mouse model of high-fat high-sucrose diet-induced obesity.Formal Name:...

Phenylpyruvic acid is an active metabolite of the essential amino acid L-phenylalanine (Cay-31498) and a biosynthetic precursor to the antifungal phenyl alkanoic acid 3-phenyllactic acid (Cay-36365). It inhibits glucose-6-phosphate dehydrogenase (G6PDH) in rat brain homogenates when used at concentrations of 0.6 and...

Phenylacetylglycine is a glycine conjugate of phenylacetate. It is formed via the conversion of phenylalanine by gut microbiota to phenylacetic acid followed by glycine conjugation in the liver. Phenylacetylglycine (100 µM) decreases hypoxia-induced apoptosis in neonatal mouse cardiomyocytes. Levels of...

3,4-Dihydroxymandelic acid is an active metabolite of the endogenous catecholamine (-)-norepinephrine (Cay-16673). It is formed from (-)-norepinephrine via the intermediate norepinephrine aldehyde by aldehyde dehydrogenase. 3,4-Dihydroxymandelic acid scavenges superoxide radicals (IC50 = 130 nM) and reduces lipid...

(+)-gamma-Tocopherol is a biologically active form of vitamin E. It inhibits the growth of DU145, LNCaP, and Caco-2 cancer cells when used at a concentration of 25 µM. In vivo, (+)-gamma-tocopherol (100 mg/kg) reduces airway eosinophil infiltration and levels of IL-6, IL-5, IL-13, and chemokine (C-C motif) ligand 2...

TMB is a colorimetric substrate for peroxidases, including hemoglobin, myeloperoxidase, and horseradish peroxidase (HRP). Enzymatic oxidation of TMB produces a radical cation followed by a diimine product that can be quantified by colorimetric detection at 652 and 450 nm, respectively, as a measure of peroxidase...

3-Phenyllactic acid is a phenyl alkanoic acid with diverse biological activities. It is active against the fungi A. flavus and A. ochraceus (MIC90s = 7.5 mg/ml for both) and various plant pathogenic fungi (MIC90s = 3.75-7.5 mg/ml). Dietary administration of 3-phenyllactic acid (0.3% w/w) improves egg laying...

3-(4-Hydroxyphenyl)lactic acid (HPLA) is a bacterial metabolite produced by L. murinus in the gut microbiome. Oral administration of HPLA with DL-3-phenylacetic acid (PLA), 2-hydroxyisocaproic acid (HICA), 2-hydroxy-3-methylbutyric acid (HMBA), and 1-indole-lactic acid (ILA) increases intestinal and white adipose...

2-Phenylacetamide is a metabolite of L-phenylalanine (Cay-31498). It increases the proliferation of MCF-7 cells, an effect that can be blocked by the estrogen receptor (ER) antagonist ICI 182780 (fulvestrant, Cay-10011269). It also increases the levels of luteinizing hormone and estrogen and the expression of...

3-Aminocatechol is a synthetic intermediate that has been used in the synthesis of vicinal diols.Formal Name: 3-amino-1,2-benzenediol. CAS Number: 20734-66-1. Synonyms: 1,2-Dihydroxy-3-aminobenzene, 2,3-Dihydroxyaniline. Molecular Formula: C6H7NO2. Formula Weight: 125.1. Purity: >95%. Formulation: (Request...