- Search results for Cay10007900
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19 products were found matching "Cay10007900"!
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Item number: Cay10007900-5
8,11,14-Eicosatriynoic acid is an inhibitor of prostaglandin and leukotriene biosynthesis as well as arachidonic acid induced platelet aggregation. It inhibits cyclooxygenase (IC50 = 14 µM), human 12-lipoxygenase (IC50 = 0.46 µM), 5-lipoxygenase (IC50 = 25 µM) and the actions of slow-reacting substance of...
Keywords: | 8,11,14-ETI, 8,11,14-eicosatriynoic acid |
Application: | COX inhibitor, 12-LO inhibitor, 5-LO inhibitor |
CAS | 34262-64-1 |
MW: | 300.4 D |
From 163.00€
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Item number: Cay35326-5
CAY10790 is a cysteinyl leukotriene 1 (CysLT1) receptor antagonist (IC50 = 2.8 µM) and G protein-coupled bile acid receptor 1 (GPBAR1) agonist. It induces receptor transactivation in HEK293T cells expressing human GPBAR1 (EC50 = 3 µM). CAY10790 (10 µM) reduces TNF-alpha and IL-1beta levels in LPS-stimulated RAW...
Keywords: | 3-(2-quinolinylmethoxy)-benzoic acid |
Application: | CysLT1 receptor antagonist, GPBAR1 agonist |
CAS | 107813-86-5 |
MW: | 279.3 D |
From 60.00€
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Item number: Cay10790-1
Muscarinic receptors are G protein-coupled acetylcholine receptors that play diverse roles. Xanomeline (oxalate) is a potent agonist of muscarinic acetylcholine receptors (EC50 values are 0.3, 92.5, 5, 52, and 42 nM for M1, M2, M3, M4, and M5, respectively). It has antipsychotic-like activities in rats and Cebus...
Keywords: | Lumeron, LY246708, Memcor, 3-[4-(hexyloxy)-1,2,5-thiadiazol-3-yl]-1,2,5,6-tetrahydro-1-methyl-pyridine, ethanedioate |
Application: | Muscarinic acetylcholine receptors agonist |
CAS | 141064-23-5 |
MW: | 371.5 D |
From 44.00€
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Item number: Cay10007907-10
Sphingosine (d18:1) is formed primarily from the breakdown of ceramide. Sphingosine inhibits protein kinase C and phosphatidic acid phosphohydrolase, whereas it activates phospholipase D and diacylglycerol (DAG) kinase. Phosphorylation of sphingosine by sphingosine kinases 1 and 2 (SPHK 1, SPHK 2) produces...
Keywords: | (-)-Sphingosine, D-erythro-Sphingosine C-18, 2S-amino-4E-octadecene-1,3R-diol |
Application: | Bioactive lipid assays |
CAS | 123-78-4 |
MW: | 299.5 D |
From 60.00€
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Item number: Cay10007902-10
Sphingosine is an amino alcohol most commonly characterized by an 18-carbon unsaturated hydrocarbon chain sphingosine (d18:1) (Cay-10007907). However, the hydrocarbon chain length of sphingosine, and the related dihydrosphingosine, can vary from 12-26 carbons in mammalian tissues. Sphingosine (d17:1) is a...
Keywords: | D-erythro-Sphingosine C-17, 2S-amino-4E-heptadecene-1,3R-diol |
Application: | Standard |
CAS | 6918-48-5 |
MW: | 285.5 D |
From 43.00€
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Item number: Cay10007901-10
Sphingosine is an amino alcohol most commonly characterized by an 18-carbon unsaturated hydrocarbon chain (Sphingosine (d18:1), Cay-10007907). However, the hydrocarbon chain length of sphingosine, and the related dihydrosphingosine, can vary from 12-26 carbons in mammalian tissues. Sphingosine (d15:1) is a...
Keywords: | D-erythro-Sphingosine C-15, 2S-amino-4E-pentadecene-1,3R-diol |
Application: | Standard |
CAS | 86555-28-4 |
MW: | 257.4 D |
From 90.00€
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Item number: Cay10007903-10
Sphingosines are long-chain base precursors of cellular sphingolipids used directly in the synthesis of ceramide, which in combination with sialic acid forms ganglioside. Sphingosine can exist in four stereoisomers, however only sphingosine occurs naturally. Compared to other sphingolipids throughout the body, which...
Keywords: | D-erythro-Sphingosine C20, 2S-amino-4E-eicosene-1,3R-diol |
Application: | Bioactive lipid assays |
CAS | 6918-49-6 |
MW: | 327.6 D |
From 44.00€
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Item number: Cay10007904-10
2-Arachidonoyl glycerol (2-AG) is an endogenous agonist of the central cannabinoid (CB1) receptor. It is present at relatively high levels in the central nervous system and is the most abundant molecular species of monoacylglycerol found in rat brain. Monoacylglycerol lipase (MAGL) hydrolyzes 2-AG to arachidonic...
Keywords: | 1-S-Arachidonoyl-1-mercapto-2,3-propanediol, 5Z,8Z,11Z,14Z-eicosatetraenyl,1-thio glycerol |
Application: | Bioactive lipid assays |
CAS | 1309664-54-7 |
MW: | 394.6 D |
From 39.00€
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Item number: Cay10007983-100
Corey lactone benzoate is a precursor that has been used in the synthesis of prostaglandins (PGs), as well as the agonist of the PGE2 receptor subtype EP4 rivenprost (Cay-13618).Formal Name: (3aR,4S,5R,6aS)-5-(benzoyloxy)hexahydro-4-(hydroxymethyl)-2H-cyclopenta[b]furan-2-one. CAS Number: 39746-00-4. Synonyms:...
Keywords: | (-)-Corey Lactone Benzoate, (-)-Corey Lactone Benzoate Alcohol,... |
Application: | Prostaglandin synthetis precursor |
CAS | 39746-00-4 |
MW: | 276.3 D |
From 35.00€
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Item number: Cay10007965-100
FK-506 is a potent immunosuppressant in the same molecular class as cyclosporin A (Cay-12088) and rapamycin (Cay-13346). Its mechanism of action involves the formation of a high affinity complex (Ki = 0.2 nM) with FK-506 binding protein 12 (FKBP12). This complex then inhibits the activity of the...
Keywords: | Tacrolimus,... |
Application: | Immunosuppressant |
CAS | 104987-11-3 |
MW: | 804 D |
From 48.00€
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Item number: Cay10007974-100
FK-506 is a potent immunosuppressant that forms a high affinity complex (Ki = 0.2 nM) with FK-506 binding protein 12 (FKBP12). This complex inhibits the activity of the calcium/calmodulin-dependent protein phosphatase, calcineurin, leading to disruption of T-cell activation. Synthetic ligand of FKBP (SLF) is a...
Keywords: | Synthetic Ligand of FKBP, 1-(3,3-dimethyl-1,2-dioxopentyl)-(2S)-2-piperidinecarboxylic acid,... |
Application: | FK-506 analog |
CAS | 195513-96-3 |
MW: | 524.7 D |
From 123.00€
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Item number: Cay10007978-100
13,14-dihydro-15-keto Prostaglandin D2-d4 (13,14-dihydro-15-keto PGD2-d4) is intended for use as an internal standard for the quantification of 13,14-dihydro-15-keto PGD2 (Cay-12610) by GC- or LC-mass spectrometry. 13,14-dihydro-15-keto PGD2 is a metabolite of PGD2 which is formed through the 15-hydroxy PGDH...
Keywords: | 13,14-dihydro-15-keto PGD2-d4, 9alpha-hydroxy-11,15-dioxo-prost-5Z-en-1-oic-3,3,4,4-d4 acid |
Application: | Standard |
MW: | 356.5 D |
From 189.00€
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