13 products were found matching "Cay10007125"!

8-Isoquinoline methanamine (hydrochloride) is a synthetic intermediate useful for pharmaceutical synthesis.Formal Name: 8-Isoquinolinemethanamine, dihydrochloride. CAS Number: 850734-84-8. Molecular Formula: C10H10N2 . 2HCl. Formula Weight: 231.1. Purity: >98%. Formulation: (Request formulation change), A...

Prostaglandin E2 (PGE2) activates four E prostanoid (EP) receptors, EP1-4. EP4 is a Gs protein-coupled receptor that, by elevating the second messenger cAMP, plays important roles in bone formation and resorption, cancer, and atherosclerosis. L-902,688 is a highly potent agonist of the human PGE2 receptor, EP4. It...

Cathepsin K is a lysosomal cysteine protease found in osteoclasts whose elevated activity has been linked to the formation of osteoporosis and arthritis. 2-cyano-Pyrimidine is a cathepsin K inhibitor whose basic structure and derivatives are being studied for the treatment of osteoporosis. 2-cyano-Pyrimidine has an...

5-Chloroesorcinol dimethyl ether is a synthetic intermediate useful for pharmaceutical synthesis.Formal Name: 1-chloro-3,5-dimethoxy-benzene. CAS Number: 7051-16-3. Synonyms: NSC 220095. Molecular Formula: C8H9ClO2. Formula Weight: 172.6. Purity: >98%. Formulation: (Request formulation change), A liquid. Solubility:...

Leukotriene D4 (LTD4) is one of the constituents of slow-reacting substance of anaphylaxis (SRS-A) produced by the metabolism of LTC4 by gamma-glutamyl transpeptidase. LTD4-induced bronchoconstriction and enhanced vascular permeability contribute to the pathogenesis of asthma and acute hypersensitivity. LTD4 is...

Leukotriene E4 (LTE4) is produced by the action of a dipeptidase on LTD4 leaving only the cysteinyl group still attached to the fatty acid backbone. It is one of the constituents of slow-reacting substance of anaphylaxis (SRS-A). LTE4 is considerably less active (8 to 12-fold) than LTC4 in the biological activities...

Leukotriene C4 (LTC4) is the parent cysteinyl-leukotriene produced by the LTC4 synthase-catalyzed conjugation of glutathione to LTA4. LTC4 is produced by neutrophils, macrophages, and mast cells, and by transcellular metabolism in platelets. It is one of the constituents of slow-reacting substance of anaphylaxis...

3-thio-Pheneacrylic acid is a synthetic intermediate useful for pharmaceutical synthesis.Formal Name: 3-(3-thienyl)-2-propenoic acid. CAS Number: 1195-52-4. Synonyms: 3-Thiophen-3-yl-Acrylic Acid. Molecular Formula: C7H6O2S. Formula Weight: 154.2. Purity: >98%. Formulation: (Request formulation change), A...

Microcystin-LA is a cyanotoxin and an inhibitor of protein phosphatase 1C (PP1C) and PP2A (IC50 = 0.3 nM for both). In vivo, microcystin-LA (7 mg/kg) induces moribundity and increases liver-to-body weight ratios and serum levels of alanine transaminase (ALT), aspartate aminotransferase (AST), and glutamate...

R-(-)-Mandelic Acid is a synthetic intermediate useful for pharmaceutical synthesis.Formal Name: alphaR-hydroxy-benzeneacetic acid. CAS Number: 611-71-2. Synonyms: D-(-)-Mandelic Acid. Molecular Formula: C8H8O3. Formula Weight: 152.2. Purity: >98%. Formulation: (Request formulation change), A crystalline solid....

(R)-(-)-2-Phenylglycinol is a synthetic intermediate useful for pharmaceutical synthesis.Formal Name: betaR-amino-benzeneethanol. CAS Number: 56613-80-0. Molecular Formula: C8H11NO. Formula Weight: 137.2. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 50 mg/ml, DMSO:...

Combrestatin A4 (CA4) is a potent inhibitor of tubulin polymerization and displays strong inhibitory activity on tumor cell growth. Combrestatin A4 was shown to inhibit tumor growth in several cell lines including IMR32 (neuroblastoma), Hs746T (gastric carcinoma), CFPAC-1 (pancreatic carcinoma), and MCF-7 (breast...