- Search results for Cay34340-0.1
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5 products were found matching "Cay34340-0.1"!
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Item number: Cay34300-1
GDC-0575 is an inhibitor of checkpoint kinase 1 (Chk1, IC50 = 1.2 nM). It is greater than 30-fold selective for Chk1 over a panel of more than 450 wild-type and mutant kinases. GDC-0575 (500 nM) enhances apoptosis induced by cytarabine (Cay-16069) in HL-60, KG-1, U937, and ML-1 human acute myeloid leukemia (AML)...
Keywords: | N-[4-[(3R)-3-amino-1-piperidinyl]-5-bromo-1H-pyrrolo[2,3-b]pyridin-3-yl]-cyclopropanecarboxamide |
Application: | Chk1 inhibitor |
CAS | 1196541-47-5 |
MW: | 378.3 D |
From 43.00€
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Item number: Cay34346-100
1-Kestose is a fructooligosaccharide that has been found in onions and has prebiotic and antidiabetic activities. It increases levels of the beneficial bacterium B. longum in diluted adult human fecal samples when added to culture broth at a concentration of 0.5% w/v. Dietary supplementation with 1-kestose increases...
Keywords: | O-beta-D-fructofuranosyl-(2->1)-beta-D-fructofuranosyl alpha-D-glucopyranoside |
Application: | Fructooligosaccharide, Prebiotic / antidiabetic agent |
CAS | 470-69-9 |
MW: | 504.4 D |
From 50.00€
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Item number: Cay34040-1
beta-Naphthoflavone is a non-carcinogenic agonist of the aryl hydrocarbon receptor (AhR). It activates transcription of the AhR target gene CYP1A1 when used at concentrations of 1 and 10 µM in HepG2 cells. beta-Naphthoflavone (10 µM) inhibits hydrogen peroxide-induced apoptosis, as well as increases the activity of...
Keywords: | 5,6-Benzoflavone, BNF, NSC 136015, 3-phenyl-1H-naphtho[2,1-b]pyran-1-one |
Application: | AhR agonist |
CAS | 6051-87-2 |
MW: | 272.3 D |
From 43.00€
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Item number: Cay30434-10
SLM6031434 is an inhibitor of sphingosine kinase 2 (SPHK2) (Ki = 0.4 µM for the recombinant mouse enzyme). It is selective for SPHK2 over SPHK1 (Kis = >20 µM). It decreases sphingosine-1-phosphate (S1P, Cay-62570) and increases sphingosine levels in U937 monocytic leukemia cells in a concentration-dependent manner....
Keywords: | (2S)-2-[3-[4-(octyloxy)-3-(trifluoromethyl)phenyl]-1,2,4-oxadiazol-5-yl]-1-pyrrolidinecarboximidamide, monohydrochloride |
Application: | SPHK2 inhibitor |
CAS | 1897379-34-8 |
MW: | 490 D |
From 69.00€
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Item number: Cay34034-10
Prunin is a polyketide synthase-derived flavonoid glycoside that has been found in G. glabra and has diverse biological activities. It inhibits neuraminidase (NA) activity in oseltamivir-sensitive and -resistant H1N1 influenza strains (IC50s = 3 and 4.53 µM, respectively). Prunin (2 µM) scavenges DPPH radicals in a...
Keywords: | Naringenin 7-O-glucoside, Naringenin 7-O-beta-D-glucopyranoside, NSC 135064,... |
Application: | Bioactive flavonoid glycoside |
CAS | 529-55-5 |
MW: | 434.4 D |
From 150.00€
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