- Search results for AG-CR1-3525
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36 products were found matching "AG-CR1-3525"!
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Item number: AG-CR1-3525-M001
Soluble in DMSO. Highly sensitive and selective fluorogenic H2S probe [1-3]. The aromatic azide moiety of AzMC is selectively reduced in the presence of H2S, producing the fluorescent 7-amino-4-methylcoumarin (AMC) with a concomitant increase in fluorescence with ?ex = 365 nm and ?em = 450 nm. Photoaffinity labeling...
Keywords: | AzMC |
Application: | Fluorogenic H2S probe |
CAS | 95633-27-5 |
MW: | 201,2 D |
From 44.00€
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Item number: AG-CR1-3553-M025
AOH1996 is an orally available and metabolically stable small molecule PCNA inhibitor, which selectively kills cancer cells, with a median concentration of about 300 nM for 50% growth inhibition. AOH1996 was not significantly toxic to non-malignant cells, even up to 10 µM. AOH1996 enhances the interaction between...
Keywords: | NSC789796, N-(2-((2-(3-Methoxyphenoxy)phenyl)amino)-2-oxoethyl)-1-naphthamide |
Application: | PCNA inhibitor |
CAS | 2089314-64-5 |
MW: | 426,5 D |
From 132.00€
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Item number: AG-CR1-3572-M025
Potent anti-cancer compound. Induces apoptosis in normal and tumor cell lines. DNA Topoisomerase II activity inhibitor. Increases Topo II-mediated DNA breakage primarily by inhibiting the ability of the enzyme to religate cleaved nucleic acid molecules. Does not lead to immediate block of DNS synthesis, induces a...
Keywords: | VP-16-213, NSC 141540 |
Application: | Apoptosis Inducer |
Host: | Semisynthetic |
CAS | 33419-42-0 |
MW: | 588,6 D |
From 33.00€
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Item number: AG-CR1-3592-M025
White to off-white powder. Soluble in DMSO or water. Slightly soluble in methanol. Insoluble in ethanol. Potent platinum-based antineoplastic agent with wide spectrum anticancer activity, Anticancer compound. Forms inter- and intrastrand DNA adducts/crosslinks, consequently blocking DNA replication and transcription...
Keywords: | Diaminocyclohexane oxalatoplatinum, 1-OHP, ACT 078, RP 54780, NSC 266046 |
Application: | Apoptosis inducer, DNA crosslinker |
CAS | 61825-94-3 |
MW: | 397,3 D |
From 22.00€
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Item number: AG-CR1-3570-M025
Antidiabetic, hypoglycemic agent. Potent and selective peroxisome proliferator-activated receptor gamma (PPAR-gamma) agonist. Potent insulin sensitizing agent binding to the PPAR receptors in fat cells and making the cells more responsive to insulin. Ameliorates insulin resistance. Improves blood pressure and...
Keywords: | BRL 49653, HSDB 7555, TDZ 01 |
Application: | PPAR-gamma agonist |
Host: | Synthetic |
CAS | 122320-73-4 |
MW: | 357,4 D |
From 33.00€
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Item number: AG-CR1-3597-M025
White to off-white solid. Soluble in DMSO, DMF, ethanol or water. Potent cell permeable and selective inhibitor of phosphatidyl-inositol 3-kinase (PI3K), Blocks class I, class II and class III PI3Ks, including some downstream targets, Blocks class I PI3K persistently and class III PI3K transiently, Induces autophagy...
Keywords: | 3-MA, 3MeA, 6-Amino-3-methylpurine, NSC 66389 |
Application: | Potent cell permeable and selective PI3 kinase inhibitor |
CAS | 5142-23-4 |
MW: | 149,2 D |
From 39.00€
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Item number: AG-CR1-3595-M025
White to off-white solid. Soluble in water, methanol, ethanol, DMSO or dimethyl formamide. Naturally occurring carnitine derivative formed by carnitine acetyltransferase during beta-oxidation of uneven chain fatty acids, with high affinity for muscular carnitine transferase. Increases cellular carnitine content,...
Keywords: | PLC |
Application: | Carnitine derivative |
CAS | 119793-66-7 |
MW: | 253,8 D |
From 66.00€
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Item number: AG-CR1-3560-M025
Potent and selective farnesoid X receptor FXR agonist (EC50= 99nM) [1]. Induces SHP in HSCs to suppress TIMP-1 expression [2]. Apoptosis inducer [2]. Protects against liver fibrosis development in rat in vivo [2]. Displays anticholeretic activity in rat in vivo [3]. Promotes preadipocyte differentiation [4]....
Keywords: | 6alpha-Ethyl-chenodeoxycholic acid, 6-alpha-ECDC, Obeticholic acid, INT-747, OCA |
Application: | FXR agonist |
CAS | 459789-99-2 |
MW: | 420,3 D |
From 66.00€
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Item number: AG-CR1-3564-M025
Potent, cell permeable, selective and ATP-competitive Rho-associated protein kinases inhibitor, including p160ROCK, ROCK-II and PRK2 inhibitor. Tumor cell invasion and metastasis suppressor. Smooth muscle relaxant. Decreases liver fibrosis by hepatic stellate cell growth inhibition. Antinociceptive. Blocks...
Keywords: | Y-27632 - 2HCL, (R)-(+)-trans-4-(1-Aminoethyl)-N-(4-pyridyl)cyclohexanecarboxamide dihydrochloride |
Application: | ROCK kinase inhibitor |
CAS | 129830-38-2 |
From 55.00€
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Item number: AG-CR1-3591-M025
White to off-white powder. Soluble in water. Potent platinum-based antineoplastic agent. Analog of cisplatin (Prod. No. AG-CR1-3590) with reduced nephrotoxicity and higher stability, Antitumor agent, Forms inter- and intrastrand DNA adducts/crosslinks, consequently blocking DNA replication and transcription and...
Keywords: | cis-Diammine(cyclobutane-1,1-dicarboxylate-O,O')platinum(II), NSC201345, NSC241240, JM-8, Paraplatin, Cbdca |
Application: | Apoptosis inducer, DNA crosslinker |
CAS | 41575-94-4 |
MW: | 371,3 D |
From 39.00€
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Item number: AG-CR1-3571-M025
Same activities as rosaglitazone (Prod. No. AG-CR1-3570) but different formulation. Antidiabetic, hypoglycemic agent. Potent and selective peroxisome proliferator-activated receptor gamma (PPAR-gamma) agonist. Potent insulin sensitizing agent binding to the PPAR receptors in fat cells and making the cells more...
Keywords: | BRL 49653C, Rosiglitazone XR, Avandia |
Application: | PPAR-gamma agonist |
Host: | Synthetic |
CAS | 155141-29-0 |
From 55.00€
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Item number: AG-CR1-3587-M025
Synthetic analog of ISP-1, isolated from Isaria sinclairii. Soluble in DMSO, ethanol or DMF. Cell permeable immunosuppressor displaying lymphocyte sequestration properties and used for treatment in multiple sclerosis. Potent sphingosine 1-phosphate (S1P) receptor (S1P1, S1P3, S1P4, and S1P5) agonist when...
Keywords: | 2-Amino-2-[2-(4-octylphenyl)ethyl]-1,3-propanediol . HCl, Fingolimod, Gilenya |
Application: | S1PR1 agonist |
CAS | 162359-56-0 |
MW: | 343,9 D |
From 17.00€
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