12 products were found matching "Cay35210-0.1"!

4'-methyl Acetyl fentanyl-d5 (hydrochloride) (exempt preparation) (Cay-35276) is an analytical reference standard intended for use as an internal standard for the quantification of 4'-methyl acetyl fentanyl (Cay-9002271, Cay-19733) by GC- or LC-MS. 4'-methyl Acetyl fentanyl is structurally similar to known opioids....

3',4'-Dihydroxyflavone is a synthetic flavonoid that has diverse biological activities. It inhibits tankyrase 1 (TNKS1) and TNKS2 (IC50s = 0.23 and 0.17 µM for the human enzymes, respectively). 3',4'-Dihydroxyflavone is active against L. donovani, T. brucei, and T. cruzi with IC50 values of 2, 1.1, and 10.1 µg/ml,...

Tesofensine is a triple monoamine reuptake inhibitor that inhibits norepinephrine, serotonin (5-HT), and dopamine reuptake function., In vivo, tesofensine (2 mg/kg, s.c.) reduces body weight and food intake in a rat model of high-fat diet-induced obesity.Formal Name:...

4-hydroxy Nonenal is a lipid peroxidation product derived from oxidized omega-6 polyunsaturated fatty acids such as arachidonic acid. 4-hydroxy Nonenal is widely used as a marker of lipid peroxidation. It exhibits various biological activities such as cytotoxicity, growth inhibiting activity, genotoxicity, and...

Piperacetazine is a typical antipsychotic. It inhibits spontaneous motor activity and responding for food in rats, as well as potentiates hexobarbital-induced narcosis in mice. It also inhibits lysosome acidification, as well as viral entry (IC50 = 98%. Formulation: (Request formulation change), A solid....

6alpha-Methylprednisolone 21-hemisuccinate is a prodrug form of the synthetic glucocorticoid methylprednisolone (Cay-15013). It is converted to methylprednisolone by carboxylesterase 2 (CES2). Nanoliposomes containing 6alpha-methylprednisolone 21-hemisuccinate decrease disease severity in a rat model of...

ERK1 and ERK2, also known as ERK1/2, are serine/threonine protein kinases and essential components of the MAP kinase signaling cascade. They share 84% sequence homology and are each composed of a glycine-rich loop, hinge region, and protein kinase domain containing a catalytic HRD motif, activation segment, and...

Thiophanate-methyl is a carbamate fungicide. It is active against a variety of fungi, including T. terrestre and G. roseum (EC50s = 98%. Formulation: (Request formulation change), A solid. Solubility: DMF: 30 mg/ml, DMSO: 30 mg/ml. lambdamax: 270 nm. SMILES: O=C(NC(NC1=C(NC(NC(OC)=O)=S)C=CC=C1)=S)OC. InChi Code:...

Perfluorooctanesulfonamide (PFOSA) is a perfluoroalkyl substance (PFAS). It induces hepatic macrophage and neutrophil accumulation and fibrosis in zebrafish larvae when administered in tank water at concentrations ranging from 0.1-100 µg/L. PFOSA has been found in municipal wastewater networks.Formal Name:...

11-dehydro-2,3-dinor Thromboxane B2-d9 (11-dehydro-2,3-dinor TXB2-d9) is intended for use as an internal standard for the quantification of 11-dehydro-2,3-dinor TXB2 (Cay-19510) by GC- or LC-MS. 11-dehydro-2,3-dinor TXB2 is a metabolite of the TXA2 inactive metabolite TXB2 (Cay-19030). It is formed from TXB2 by...

Placental alkaline phosphatase (PLAP) is the placenta-specific isoenzyme of AP encoded by the ALPP gene in humans. It exists as a homodimer where each monomer is composed of an N-terminal alpha-helix and a crown domain that stabilize PLAP homodimers, a Zn2+- and Mg2+-containing active site with a catalytic serine...

N-Methylcytisine is an alkaloid that has been found in L. albus and has diverse biological activities. It is an agonist of nicotinic acetylcholine receptors (nAChRs) and selectively binds to nAChRs over muscarinic acetylcholine receptors (mAChRs, IC50s = 0.05 and 417 µM, respectively). It elicits whole-cell currents...