10 products were found matching "Cay35200-0.1"!

Desmethyl ranolazine is a metabolite of the antianginal agent ranolazine (Cay-15604). It is formed from ranolazine by the cytochrome P450 (CYP) isoform CYP3A.Formal Name: N-(2,6-dimethylphenyl)-4-[2-hydroxy-3-(2-hydroxyphenoxy)propyl]-1-piperazineacetamide. CAS Number: 172430-45-4. Synonyms: CVT-2514, RS 88390....

ML-154 is an antagonist of the neuropeptide S receptor (NPSR, IC50 = 3.5 nM). It is selective for NPSR over arginine vasopressin (AVP) receptor V1B, as well as a panel of 55 receptors, channels, and transporters at 10 µM. ML-154 reduces NPS-induced calcium mobilization, cAMP formation, and ERK activation with IC50...

ERK1 and ERK2, also known as ERK1/2, are serine/threonine protein kinases and essential components of the MAP kinase signaling cascade. They share 84% sequence homology and are each composed of a glycine-rich loop, hinge region, and protein kinase domain containing a catalytic HRD motif, activation segment, and...

Thiophanate-methyl is a carbamate fungicide. It is active against a variety of fungi, including T. terrestre and G. roseum (EC50s = 98%. Formulation: (Request formulation change), A solid. Solubility: DMF: 30 mg/ml, DMSO: 30 mg/ml. lambdamax: 270 nm. SMILES: O=C(NC(NC1=C(NC(NC(OC)=O)=S)C=CC=C1)=S)OC. InChi Code:...

Piperacetazine is a typical antipsychotic. It inhibits spontaneous motor activity and responding for food in rats, as well as potentiates hexobarbital-induced narcosis in mice. It also inhibits lysosome acidification, as well as viral entry (IC50 = 98%. Formulation: (Request formulation change), A solid....

Iodixanol is a nonionic, water-soluble contrast reagent. It induces apoptosis and mitophagy in renal epithelial cells in a rat model of contrast-induced acute kidney injury. Iodixanol has also been used as a density gradient medium in the fractionation of plasma lipoproteins. Formulations containing iodixanol have...

Continentalic acid is a diterpenic acid that has been found in A. continentalis and has diverse biological activities. It is active against methicillin-susceptible S. aureus (MSSA) and clinical isolates of methicillin-resistant S. aureus (MRSA, MICs = 8 and 8-16 µg/ml, respectively). Continentalic acid (200 µM)...

STING agonist 1a is an agonist of stimulator of interferon genes (STING). It induces expression of an IRF-inducible SEAP reporter gene in a cell-based assay (EC50 = 16.77 µM). STING agonist 1a (12.5-100 µM) induces expression of IFN-beta, IL-6, and chemokine (C-X-C motif) ligand 10 (CXCL10) in THP-1 cells, an effect...

6beta-hydroxy Prednisolone is a metabolite of prednisolone (Cay-20866), the active metabolite of prednisone (Cay-20677). It is formed from prednisolone primarily by the cytochrome P450 (CYP) isoform CYP3A4 and to a lesser extent by CYP3A5.Formal Name: 6beta,11beta,17,21-tetrahydroxy-pregna-1,4-diene-3,20-dione. CAS...

CPI-637 is an inhibitor of cyclic-AMP response element binding protein (CBP) and adenoviral E1A binding protein of 300 kDa (EP300), a homologous pair of bromodomain-containing proteins (IC50s = 30 and 51 nM in a time-resolved-FRET (TR-FRET) assay). It is selective for CBP and EP300 over the BET family of...