- Search results for Cay10007252-25
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10 products were found matching "Cay10007252-25"!
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Item number: Cay10007295-25
Anandamide (AEA) is an endogenous cannabinoid that binds to both central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptors. The biological actions of AEA are terminated by cellular uptake and hydrolysis of the amide bond by the enzyme fatty acid amide hydrolase (FAAH). Anandamide (AEA) is an endogenous...
Keywords: | Arachidonamide, Arachidonic Acid amide, 5Z,8Z,11Z,14Z-eicosatetraenamide |
Application: | Bioactive lipid assays |
CAS | 85146-53-8 |
MW: | 303.5 D |
From 56.00€
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Item number: Cay10007452-25
Vinclozolin M2 is an active metabolite of vinclozolin (Cay-23939). It is formed from vinclozolin by successive esterase activity and decarboxylation of vinclozolin in C. elegans and by decarboxylation in human liver microsomes. Vinclozolin M2 is an antagonist of the mineralocorticoid receptor (IC50 = 1,400 nM) and...
Keywords: | M2, N-(3,5-dichlorophenyl)-2-hydroxy-2-methyl-3-butenamide |
Application: | Dicarboximide fungicide, rat androgen receptor antagonist |
CAS | 83792-61-4 |
MW: | 260.1 D |
From 65.00€
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Item number: Cay17002-25
PIK-III is an inhibitor of the type 3 phosphatidylinositol 3-kinase (PI3K) vacuolar protein sorting 34 (Vps34) that binds a unique hydrophobic pocket (IC50 = 18 nM). It is selective for Vps34 over related PI3K isoforms, PI4Kbeta, and mTOR. PIK-III acutely inhibits autophagy and de novo lipidation of LC3, leading to...
Keywords: | Vacuolar Protein Sorting 34 Inhibitor 2, Vps34 Inhibitor 2, Vps34-IN2,... |
Application: | VPS34 inhibitor |
CAS | 1383716-40-2 |
MW: | 319.4 D |
From 100.00€
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Item number: Cay10057-25
Soluble guanylate cyclase (sGC), a receptor for nitric oxide (NO), is a heterodimer consisting of alpha and beta subunits, with the beta subunit featuring a heme-nitric oxide (H-NOX) binding domain. The binding of NO to H-NOX induces sGC to generate the second messenger cGMP. BAY 41-2272 is a pyrazolopyridine...
Keywords: | 5-cyclopropyl-2-[1-[(2-fluorophenyl)methyl]-1H-pyrazolo[3,4-b]pyridin-3-yl]-4-pyrimidinamine |
Application: | Soluble guanylate cyclase activator |
CAS | 256376-24-6 |
MW: | 360.4 D |
From 142.00€
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Item number: Cay10007902-25
Sphingosine is an amino alcohol most commonly characterized by an 18-carbon unsaturated hydrocarbon chain sphingosine (d18:1) (Cay-10007907). However, the hydrocarbon chain length of sphingosine, and the related dihydrosphingosine, can vary from 12-26 carbons in mammalian tissues. Sphingosine (d17:1) is a...
Keywords: | D-erythro-Sphingosine C-17, 2S-amino-4E-heptadecene-1,3R-diol |
Application: | Standard |
CAS | 6918-48-5 |
MW: | 285.5 D |
From 43.00€
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Item number: Cay10007912-25
20-carboxy Arachidonic acid (20-COOH-AA) is the major metabolite of 20-HETE that is produced in renal tubular epithelial, endothelial, and microvascular smooth muscle cell cultures. This omega-oxidation conversion can take place using purified alcohol dehydrogenases three and four or by microsomes containing...
Keywords: | 20-carboxy AA, 20-COOH-AA, 5Z,8Z,11Z,14Z-eicosatetraenedioic acid |
Application: | Bioactive lipid assays |
CAS | 79551-84-1 |
MW: | 334.5 D |
From 300.00€
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Item number: Cay10007662-25
L-Biopterin is the oxidized form of tetrahydro-L-biopterin (BH4), a nitric oxide synthase (NOS) cofactor. L-Biopterin can be reduced to BH4 via thioredoxin reductase followed by dihydropteridine reductase or reduced glutathione. It is extremely toxic to human melanocytes in culture (IC50 = 0.2 µM after 48 hrs)....
Keywords: | L-erythro-Biopterin, NSC 339699, 2-amino-6-[(1R,2S)-1,2-dihydroxypropyl]-4(1H)-pteridinone |
Application: | NOS cofactor |
CAS | 22150-76-1 |
MW: | 237.2 D |
From 53.00€
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Item number: Cay10007412-25
Combrestatin A4 (CA4) is a potent inhibitor of tubulin polymerization and displays strong inhibitory activity on tumor cell growth. Combrestatin A4 was shown to inhibit tumor growth in several cell lines including IMR32 (neuroblastoma), Hs746T (gastric carcinoma), CFPAC-1 (pancreatic carcinoma), and MCF-7 (breast...
Keywords: | CA4, Combretastatin A4, CRC 87-09, 2-methoxy-5-[(1Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]-phenol |
Application: | Tubulin polymerization inhibitor |
CAS | 117048-59-6 |
MW: | 316.4 D |
From 85.00€
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Item number: Cay10007132-25
(R)-(-)-2-Phenylglycinol is a synthetic intermediate useful for pharmaceutical synthesis.Formal Name: betaR-amino-benzeneethanol. CAS Number: 56613-80-0. Molecular Formula: C8H11NO. Formula Weight: 137.2. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 50 mg/ml, DMSO:...
Keywords: | betaR-amino-benzeneethanol |
Application: | Synthetic intermediate, pharmaceutical synthesis |
CAS | 56613-80-0 |
MW: | 137.2 D |
From 22.00€
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Item number: Cay10007012-25
12-oxo Stearic acid methyl ester is an esterified form of 12-oxo stearic acid. It has been found in esterified L. chinensis and L. decipiens pulp oils and serves as a measure of 12-oxo stearic acid content.Formal Name: 12-oxo-octadecanoic acid, methyl ester. CAS Number: 2380-27-0. Synonyms: Methyl 12-oxo...
Keywords: | Methyl 12-keto Stearate, Methyl 12-oxo Octadecanoate, Methyl 12-oxo Stearate, 12-oxo-octadecanoic acid, methyl ester |
CAS | 2380-27-0 |
MW: | 312.5 D |
From 88.00€
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