- Search results for Cay10007255-50
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9 products were found matching "Cay10007255-50"!
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Item number: Cay10007055-5
3-keto Petromyzonol is a synthetic intermediate useful for pharmaceutical synthesis.Formal Name: 7alpha,12alpha,24-trihydroxy-5alpha-cholane-3-one. CAS Number: 359436-56-9. Molecular Formula: C24H40O4. Formula Weight: 392.6. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility:...
Keywords: | 7alpha,12alpha,24-trihydroxy-5alpha-cholane-3-one |
Application: | Synthetic intermediate, Pharmaceutical synthesis |
CAS | 359436-56-9 |
MW: | 392.6 D |
From 76.00€
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Item number: Cay10007295-50
Anandamide (AEA) is an endogenous cannabinoid that binds to both central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptors. The biological actions of AEA are terminated by cellular uptake and hydrolysis of the amide bond by the enzyme fatty acid amide hydrolase (FAAH). Anandamide (AEA) is an endogenous...
Keywords: | Arachidonamide, Arachidonic Acid amide, 5Z,8Z,11Z,14Z-eicosatetraenamide |
Application: | Bioactive lipid assays |
CAS | 85146-53-8 |
MW: | 303.5 D |
From 56.00€
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Item number: Cay10007542-50
Biotin is a growth factor that plays an important role in numerous reactions that are critical to microorganisms, plants, and animals. Biotin has a strong affinity for the protein avidin, a trait that has been utilized for many assay reporter applications. Biotin is a growth factor that plays an important role in...
Keywords: | 7-keto-8-Aminopelargomic Acid, 8-amino-7-oxo-nonanoic acid, monohydrochloride |
Application: | Bioactive lipid assays |
CAS | 177408-65-0 |
MW: | 223.7 D |
From 22.00€
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Item number: Cay10007452-50
Vinclozolin M2 is an active metabolite of vinclozolin (Cay-23939). It is formed from vinclozolin by successive esterase activity and decarboxylation of vinclozolin in C. elegans and by decarboxylation in human liver microsomes. Vinclozolin M2 is an antagonist of the mineralocorticoid receptor (IC50 = 1,400 nM) and...
Keywords: | M2, N-(3,5-dichlorophenyl)-2-hydroxy-2-methyl-3-butenamide |
Application: | Dicarboximide fungicide, rat androgen receptor antagonist |
CAS | 83792-61-4 |
MW: | 260.1 D |
From 65.00€
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Item number: Cay10005276-50
DL-threo PDMP is a mixture of ceramide analogs that contains two of the four possible stereoisomers of PDMP (Cay-62595): D-threo-(1R,2R)-PDMP and L-threo-(1S,2S)-PDMP. DL-threo-PDMP inhibits glucosylceramide synthase by 33 and 48% in MDCK cell homogenates when used at concentrations of 5 and 10 µM. It reduces the...
Keywords: | N-[2-hydroxy-1-(4-morpholinylmethyl)-2-phenylethyl]-decanamide, monohydrochloride |
Application: | Bioactive lipid assays |
CAS | 80938-69-8 |
MW: | 427 D |
From 85.00€
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Item number: Cay10007125-500
8-Isoquinoline methanamine (hydrochloride) is a synthetic intermediate useful for pharmaceutical synthesis.Formal Name: 8-Isoquinolinemethanamine, dihydrochloride. CAS Number: 850734-84-8. Molecular Formula: C10H10N2 . 2HCl. Formula Weight: 231.1. Purity: >98%. Formulation: (Request formulation change), A...
Keywords: | 8-Isoquinolinemethanamine, dihydrochloride |
Application: | Synthetic intermediate, Pharmaceutical synthesis |
CAS | 850734-84-8 |
MW: | 231.1 D |
From 189.00€
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Item number: Cay10057-50
Soluble guanylate cyclase (sGC), a receptor for nitric oxide (NO), is a heterodimer consisting of alpha and beta subunits, with the beta subunit featuring a heme-nitric oxide (H-NOX) binding domain. The binding of NO to H-NOX induces sGC to generate the second messenger cGMP. BAY 41-2272 is a pyrazolopyridine...
Keywords: | 5-cyclopropyl-2-[1-[(2-fluorophenyl)methyl]-1H-pyrazolo[3,4-b]pyridin-3-yl]-4-pyrimidinamine |
Application: | Soluble guanylate cyclase activator |
CAS | 256376-24-6 |
MW: | 360.4 D |
From 142.00€
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Item number: Cay10007205-1
GPR40 is a seven transmembrane G Protein-coupled receptor with signalling mediated by medium- and long-chain fatty acids. Found predominantly in the beta-cells of pancreatic islets, it has been implicated in the regulation of insulin secretion. Overexpression of GPR40 in mouse beta cells leads to glucose intolerance...
Keywords: | Anti-FFAR1, Anti-GPR40, Anti-Free fatty acid receptor 1, Anti-Free fatty acid receptor 1, Anti-G-protein coupled receptor... |
Application: | IHC, WB |
Host: | Rabbit |
Species reactivity: | human |
422.00€
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Item number: Cay17055-50
KD 025 is an inhibitor of Rho-associated kinase 2 (ROCK2, IC50 = 0.105 µM). It is selective for ROCK2 over ROCK1 (IC50 = 24 µM). KD 025 (10 µM) decreases the expression of connective tissue growth factor (CTGF) and induces remodeling of the actin cytoskeleton in isolated human ileal fibrotic smooth muscle cells. It...
Keywords: | SLx-2119, 2-[3-[4-(1H-indazol-5-ylamino)-2-quinazolinyl]phenoxy]-N-(1-methylethyl)-acetamide |
Application: | ROCK2 inhibitor |
CAS | 911417-87-3 |
MW: | 452.5 D |
From 75.00€
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