- Search results for Cay10007255-25
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4 products were found matching "Cay10007255-25"!
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Item number: Cay10007295-25
Anandamide (AEA) is an endogenous cannabinoid that binds to both central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptors. The biological actions of AEA are terminated by cellular uptake and hydrolysis of the amide bond by the enzyme fatty acid amide hydrolase (FAAH). Anandamide (AEA) is an endogenous...
Keywords: | Arachidonamide, Arachidonic Acid amide, 5Z,8Z,11Z,14Z-eicosatetraenamide |
Application: | Bioactive lipid assays |
CAS | 85146-53-8 |
MW: | 303.5 D |
From 56.00€
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Item number: Cay17055-25
KD 025 is an inhibitor of Rho-associated kinase 2 (ROCK2, IC50 = 0.105 µM). It is selective for ROCK2 over ROCK1 (IC50 = 24 µM). KD 025 (10 µM) decreases the expression of connective tissue growth factor (CTGF) and induces remodeling of the actin cytoskeleton in isolated human ileal fibrotic smooth muscle cells. It...
Keywords: | SLx-2119, 2-[3-[4-(1H-indazol-5-ylamino)-2-quinazolinyl]phenoxy]-N-(1-methylethyl)-acetamide |
Application: | ROCK2 inhibitor |
CAS | 911417-87-3 |
MW: | 452.5 D |
From 75.00€
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Item number: Cay10057-25
Soluble guanylate cyclase (sGC), a receptor for nitric oxide (NO), is a heterodimer consisting of alpha and beta subunits, with the beta subunit featuring a heme-nitric oxide (H-NOX) binding domain. The binding of NO to H-NOX induces sGC to generate the second messenger cGMP. BAY 41-2272 is a pyrazolopyridine...
Keywords: | 5-cyclopropyl-2-[1-[(2-fluorophenyl)methyl]-1H-pyrazolo[3,4-b]pyridin-3-yl]-4-pyrimidinamine |
Application: | Soluble guanylate cyclase activator |
CAS | 256376-24-6 |
MW: | 360.4 D |
From 142.00€
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Item number: Cay10075-25
Inhibitors of cyclooxygenase (COX) are generally grouped according to selectivity for COX-1 versus COX-2. However, many COX inhibitors also show an antitumor, pro-apoptotic activity that is distinct from COX inhibition - celecoxib is an example. CAY10452 is a celecoxib analog that retains potent, selective COX-2...
Keywords: | PTPBS, 4-[5-phenyl-3-(trifluoromethyl)-1H-pyrazol-1-yl]-benzenesulfonamide |
Application: | COX-2 inhibitor |
CAS | 170569-87-6 |
MW: | 367.3 D |
From 43.00€
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