6 products were found matching "Cay10007255-100"!

15(S)-HETE is a major arachidonic acid metabolite from the 15-lipoxygenase pathway. In mammals, 15(S)-HETE is synthesized in the respiratory epithelium, leukocytes, and reticulocytes. 15(S)-HETE is present in µg/ml concentrations in the nasal secretions of allergic rhinitis. 15(S)-HETE MaxSpec(R) standard is a...

GPR40 is a seven transmembrane G Protein-coupled receptor with signalling mediated by medium- and long-chain fatty acids. Found predominantly in the beta-cells of pancreatic islets, it has been implicated in the regulation of insulin secretion. Overexpression of GPR40 in mouse beta cells leads to glucose intolerance...

Fatty acid binding protein 1 (FABP1) is one of nine known cytosolic FABPs ranging in size from 14-15 kDa containing 127-132 amino acids. FABP1 is composed of ten antiparallel beta strands that form a barrel with a bigger binding pocket than the other FABPs allowing it to accommodate two fatty acids. Expression of...

3-keto Petromyzonol is a synthetic intermediate useful for pharmaceutical synthesis.Formal Name: 7alpha,12alpha,24-trihydroxy-5alpha-cholane-3-one. CAS Number: 359436-56-9. Molecular Formula: C24H40O4. Formula Weight: 392.6. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility:...

8-Isoquinoline methanamine (hydrochloride) is a synthetic intermediate useful for pharmaceutical synthesis.Formal Name: 8-Isoquinolinemethanamine, dihydrochloride. CAS Number: 850734-84-8. Molecular Formula: C10H10N2 . 2HCl. Formula Weight: 231.1. Purity: >98%. Formulation: (Request formulation change), A...

KD 025 is an inhibitor of Rho-associated kinase 2 (ROCK2, IC50 = 0.105 µM). It is selective for ROCK2 over ROCK1 (IC50 = 24 µM). KD 025 (10 µM) decreases the expression of connective tissue growth factor (CTGF) and induces remodeling of the actin cytoskeleton in isolated human ileal fibrotic smooth muscle cells. It...