5 products were found matching "Cay10007276-25"!
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Resolvin D2
Item number: Cay10007279-25
Resolvins are a family of potent lipid mediators derived from both eicosapentaenoic acid (EPA, Cay-90110) and docosahexaenoic acid (DHA, Cay-90310). In addition to being anti-inflammatory, resolvins promote the resolution of the inflammatory response back to a non-inflamed state. Resolvin D2 (RvD2) is produced...
| Keywords: | 7(S),16(R),17(S)-Resolvin D2, RvD2, 7S,16R,17S-trihydroxy-4Z,8E,10Z,12E,14E,19Z-docosahexaenoic acid |
| Application: | Lipid mediator |
| CAS | 810668-37-2 |
| MW: | 376.5 D |
From 205.00€
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PD 169316
Item number: Cay10006727-25
p38 is a member of the mitogen-activated protein kinase (MAPK) superfamily of enzymes that play an important role in signal transduction. PD 169316 is a selective inhibitor of p38 MAPK. It inhibits p38 MAPK with an IC50 of 89 nM, whereas the IC50s are >100-fold higher for extracellular signal-regulated kinase (ERK)...
| Keywords: | 4-[5-(4-fluorophenyl)-2-(4-nitrophenyl)-1H-imidazol-4-yl]-pyridine |
| Application: | p38 MAPK inhibitor |
| CAS | 152121-53-4 |
| MW: | 360.3 D |
From 84.00€
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CAY10494
Item number: Cay10007126-250
CAY10494 is a synthetic intermediate useful for pharmaceutical synthesis.Formal Name: 4-[(4-thieno[2,3-c]pyridin-7-yl-1-piperazinyl)methyl]-benzoic acid, 1,1-dimethylethyl ester. CAS Number: 1044764-15-9. Molecular Formula: C23H27N3O2S. Formula Weight: 409.6. Purity: >98%. Formulation: (Request formulation change),...
| Keywords: | 4-[(4-thieno[2,3-c]pyridin-7-yl-1-piperazinyl)methyl]-benzoic acid, 1,1-dimethylethyl ester |
| Application: | Synthetic intermediate, pharmaceutical synthesis |
| CAS | 1044764-15-9 |
| MW: | 409.6 D |
From 77.00€
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Inflachromene
Item number: Cay17006-25
Inflachromene is an anti-inflammatory agent that directly binds high mobility group protein 1 (HMGB1) and HMGB2 and reduces their cytoplasmic accumulation in microglial cells. It is functional in vivo, downregulating proinflammatory functions of HMGB proteins and reducing neuronal damage. Inflachromene also...
| Keywords: | ICM, 5,12b-dihydro-10-hydroxy-7,7-dimethyl-2-phenyl-1H,7H-[1]benzopyrano[4,3-c][1,2,4]triazolo[1,2-a]pyridazine-1,3(2H)-dione |
| Application: | Microglial inhibitor |
| CAS | 908568-01-4 |
| MW: | 377.4 D |
From 179.00€
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DL-threo-PDMP (hydrochloride)
Item number: Cay10005276-10
DL-threo PDMP is a mixture of ceramide analogs that contains two of the four possible stereoisomers of PDMP (Cay-62595): D-threo-(1R,2R)-PDMP and L-threo-(1S,2S)-PDMP. DL-threo-PDMP inhibits glucosylceramide synthase by 33 and 48% in MDCK cell homogenates when used at concentrations of 5 and 10 µM. It reduces the...
| Keywords: | N-[2-hydroxy-1-(4-morpholinylmethyl)-2-phenylethyl]-decanamide, monohydrochloride |
| Application: | Bioactive lipid assays |
| CAS | 80938-69-8 |
| MW: | 427 D |
From 85.00€
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