5-Iodotubercidin

5-Iodotubercidin
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay10010375-500 500 µg -

6 - 10 business days*

76.00€
Cay10010375-1 1 mg -

6 - 10 business days*

142.00€
Cay10010375-5 5 mg -

6 - 10 business days*

443.00€
 
5-Iodotubercidin is an inhibitor of adenosine kinase (IC50 = 0.026 µM). It inhibits protein... more
Product information "5-Iodotubercidin"
5-Iodotubercidin is an inhibitor of adenosine kinase (IC50 = 0.026 µM). It inhibits protein kinase A (PKA), phosphorylase kinase, casein kinase 1 (CK1), CK2, and PKC (IC50s = 5-10, 5-10, 0.4, 10.9, and 0.4 µM, respectively). 5-Iodotubercidin is also an inhibitor of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA-dependent RNA polymerase (RdRp, EC50 = 0.75 µM). It decreases fatty acid synthesis and increases fatty acid oxidation in isolated rat hepatocytes when used at a concentration of 20 µM. In vivo, 5-iodotubercidin reduces the number of seizures in a rat model of seizures induced by maximum electroshock (MES, ED50 = 6 mg/kg).Formal Name: 5-iodo-7-beta-D-ribofuranosyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine. CAS Number: 24386-93-4. Synonyms: Itu, NSC 113939. Molecular Formula: C11H13IN4O4. Formula Weight: 392.2. Purity: >95%. Formulation: (Request formulation change), A solid. Solubility: DMSO: 10 mg/ml. lambdamax: 207, 284 nm. SMILES: IC1=CN([C@H]2[C@H](O)[C@H](O)[C@@H](CO)O2)C3=C1C(N)=NC=N3. InChi Code: InChI=1S/C11H13IN4O4/c12-4-1-16(10-6(4)9(13)14-3-15-10)11-8(19)7(18)5(2-17)20-11/h1,3,5,7-8,11,17-19H,2H2,(H2,13,14,15)/t5-,7-,8-,11-/m1/s1. InChi Key: WHSIXKUPQCKWBY-IOSLPCCCSA-N.
Keywords: Itu, NSC 113939, 5-iodo-7-beta-D-ribofuranosyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine
Supplier: Cayman Chemical
Supplier-Nr: 10010375

Properties

Application: MAPK Inhibitor
MW: 392.2 D
Formula: C11H13IN4O4
Purity: >95%
Format: Solution

Database Information

CAS : 24386-93-4| Matching products

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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