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Harringtonine
Item number: Cay15361-1
Harringtonine is a natural alkaloid that inhibits protein synthesis at low micromolar concentrations. It immobilizes ribosomes immediately after the initiation of translation. While harringtonine has drawn some interest in mitigating cancer, its homolog homoharrington is more effective, particularly for chronic...
| Keywords: | NSC 124147, 3-[4-methyl (2R)-2-hydroxy-2-(3-hydroxy-3-methylbutyl)butanedioate]cephalotaxine |
| Application: | Protein synthesis inhibitor |
| CAS | 26833-85-2 |
| MW: | 531.6 D |
From 60.00€
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Butein
Item number: Cay15371-1
Butein is a plant polyphenol that is classified as a chalcone, due to the propenone linkage between the phenol groups. Like other polyphenols, butein is a potent antioxidant and affects the numerous pathways modulated by oxidant tone, including inflammation, cancer, and immune response. It inhibits 5-lipoxygenase,...
| Keywords: | 2',3,4,4'-tetrahydroxy Chalcone, (2E)-1-(2,4-dihydroxyphenyl)-3-(3,4-dihydroxyphenyl)-2-propen-1-one |
| Application: | Potent antioxidant, 5-lipoxygenase inhibitor |
| CAS | 487-52-5 |
| MW: | 272.3 D |
From 43.00€
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Wortmannin-Rapamycin Conjugate
Item number: Cay13671-1
Phosphoinositide 3-kinase (PI3K) and mammalian target of rapamycin (mTOR) act synergistically in promoting cancer. Wortmannin is a potent inhibitor of PI3K enzymes, while rapamycin blocks mTOR Complex 1 TORC1. Wortmannin-rapamycin conjugate consists of analogs of 17-hydroxy wortmannin and rapamycin conjugated via a...
| Keywords: | 1-(4S,4aR,5R,6aS,7S,9aR,E)-1-(((3-(dimethylamino)propyl)(methyl)amino)methylene)-7,11-dihydroxy-4-(methoxymethyl)-4a,6a-di... |
| Application: | PI3K/TORC1 inhibitors |
| CAS | 1067892-47-0 |
| MW: | 1598.9 D |
From 204.00€
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