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(±)5-HETE lactone
(±)5-HETE lactone

Item number: Cay34215-50

(±)5-HETE lactone is a cyclic ester formed by acid-catalyzed nucleophilic addition of the C-5 hydroxyl to the C-1 carboxyl of (±)5-HETE. (±)5-HETE lactone is an inhibitor of 5-lipoxygenase from rat basophilic leukemia cells with an IC50 of 27 µM. The lactone is several times more potent than the linear...
Keywords: (±)5-hydroxy-6E,8Z,11Z,14Z-eicosatetraenoic acid, 1,5-lactone
Application: 5-LO inhibitor
CAS 73279-37-5
MW: 302.5 D
From 92.00€ *
Review
(±)5-HETE
(±)5-HETE

Item number: Cay34210-50

(±)5-HETE is one of the six monohydroxy fatty acids produced by the non-enzymatic oxidation of arachidonic acid. It contains equal amounts of 5(S)-HETE and 5(R)-HETE. (±)5-HETE induces the aggregation of isolated neutrophils with an IC50 value of 200 nM.Formal Name: (±)5-hydroxy-6E,8Z,11Z,14Z-eicosatetraenoic acid....
Keywords: (±)5-hydroxy-6E,8Z,11Z,14Z-eicosatetraenoic acid
Application: Bioactive lipid studies
CAS 73307-52-5
MW: 320.5 D
From 97.00€ *
Review