- Search results for Cay11102
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6 products were found matching "Cay11102"!
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Item number: Cay11102-500
The lysine methyltransferase EZH2 (KMT6), part of the polycomb repressive complex 2, catalyzes trimethylation of lysine 27 on histone H3 and is involved in proliferation and aggressive cell growth associated with neoplastic cells. 3-Deazaneplanocin A is a cyclopentenyl analog of 3-deazaadenosine, originally...
Keywords: | 2,3-DMMC, 5R-(4-amino-1H-imidazo[4,5-c]pyridin-1-yl)-3-(hydroxymethyl)-3-cyclopentene-1S,2R-diol, monohydrochloride |
CAS | 120964-45-6 |
MW: | 298.7 D |
From 123.00€
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Item number: Cay11022-10
BIBF 1120 is an inhibitor of the receptor tyrosine kinases VEGFR, FGFR, and PDGFR (IC50s = 13-34, 37-610, 59, and 65 nM for VEGFR1-3, FGFR1-4, PDGFRalpha, and PDGFRbeta, respectively). It is selective for VEGFR, FGFR, and PDGFR over a panel of 33 kinases but does inhibit FLT3, LCK, LYN, and Src (IC50s = 16-156 nM)....
Keywords: | Nintedanib,... |
Application: | Receptor tyrosine kinase inhibitor |
CAS | 656247-17-5 |
MW: | 539.6 D |
From 60.00€
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Item number: Cay10022-50
F16 is a small, cationic, lipophilic molecule which binds preferentially to mitochondrial membranes and disrupts their function. F16 was discovered in high throughput screens for tumor inhibitors, where it was found to induce apoptosis in HER-1/EGFR-expressing breast carcinoma cell lines. In addition to being a...
Keywords: | 4-[(1E)-2-(1H-indol-3-yl)ethenyl]-1-methyl-pyridinium iodide |
Application: | Antitumor agent, Apoptosis inducer |
CAS | 36098-33-6 |
MW: | 362.2 D |
From 19.00€
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Item number: Cay100022-1
Hepsin is a type II membrane-associated protein that has an extracellular proteolytic domain and exhibits low sequence homology to other known proteases. Hepsin overexpression is observed in prostate, breast, kidney, and ovarian cancers and due to low homology to other known proteases may provide a unique target for...
Keywords: | Anti-HPN, Anti-TMPRSS1, Anti-Serine protease hepsin, Anti-Transmembrane protease serine 1, Anti-Serine protease hepsin... |
Application: | IHC (paraffin), WB |
Host: | Rabbit |
Species reactivity: | human |
422.00€
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Item number: Cay100002-1
Optineurin (originally named FIP-2) is a 74 kDa protein implicated in signal transduction of the tumor necrosis factor (TNF) pathway as well as membrane traffic regulation and cellular morphogenesis. Optineurin protein is also involved in apoptosis, although the exact role is currently unknown. Increased apoptosis...
Keywords: | Anti-OPTN, Anti-FIP2, Anti-FIP-2, Anti-HIP-7, Anti-FIP-2, Anti-HIP-7, Anti-Optineurin, Anti-Optineurin, Anti-TFIIIA-IntP,... |
Application: | IHC, WB |
Host: | Rabbit |
Species reactivity: | human |
422.00€
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Item number: Cay10002-1
This mixture contains primary prostaglandins produced from arachidonic acid and dihomo-gamma-linolenic acid. Contents: Prostaglandin E1, Prostaglandin E2, Prostaglandin F1alpha, 6-keto Prostaglandin F1alpha, and Prostaglandin F2alpha (100 µg each).Synonyms: PG HPLC Mixture. Purity: >98% for each compound....
Keywords: | PG HPLC Mixture |
Application: | Bioactive lipid assays |
113.00€
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