3-Deaza-2'-deoxyadenosine

3-Deaza-2'-deoxyadenosine strongly inhibits lymphocyte-mediated cytolysis with low cytotoxicity when applied at 100 µM. This nucleoside can also be used to evaluate the role of the adenine N3 nitrogen in DNA structure and function.Formal Name: 1-(2-deoxy-beta-D-erythro-pentofuranosyl)-1H-imidazo[4,5-c]pyridin-4-amine. CAS Number: 78582-17-9. Synonyms: c3dA. Molecular Formula: C11H14N4O3. Formula Weight: 250.3. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 5 mg/ml, DMSO: 20 mg/ml, PBS (pH 7.2): 10 mg/ml. lambdamax: 212, 266 nm. SMILES: NC1=C2C(N([C@H]3C[C@H](O)[C@@H](CO)O3)C=N2)=CC=N1. InChi Code: InChI=1S/C11H14N4O3/c12-11-10-6(1-2-13-11)15(5-14-10)9-3-7(17)8(4-16)18-9/h1-2,5,7-9,16-17H,3-4H2,(H2,12,13)/t7-,8+,9+/m0/s1. InChi Key: KMQPIRJQPAVGJL-DJLDLDEBSA-N.