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RKI-1447
Item number: Cay16278-5
RKI-1447 is an inhibitor of the Rho-associated kinases ROCK1 and 2 (IC50s = 14.5 and 6.2 nM, respectively) that functions by binding to the ATP binding site of the kinase. In cancer cells, RKI-1447 at a concentration of 100 nM has been found to suppress the activation of ROCK substrates myosin light chain (MLC)-2...
| Keywords: | N-[(3-hydroxyphenyl)methyl]-N'-[4-(4-pyridinyl)-2-thiazolyl]-urea |
| Application: | ROCK inhibitor |
| CAS | 1342278-01-6 |
| MW: | 326.4 D |
From 82.00€
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Anti-BGLAP
Item number: E-AB-16278.120
Bone gamma-carboxyglutamic acid (Gla) protein, known as BGLAP, BGP or osteocalcin, is an abundant, non-collagenous protein component of bone that is produced by osteoblasts. In mice, osteocalcin is composed of a cluster of 3 genes known as OG1, OG2 and ORG, all of which can be found within a 23Kb span of genomic...
| Keywords: | Anti-BGP, Anti-BGLAP, Anti-Osteocalcin, Anti-Bone Gla protein, Anti-Gamma-carboxyglutamic acid-containing protein, BGLAP... |
| Application: | IHC, ELISA |
| Host: | Rabbit |
| Species reactivity: | human |
From 71.00€
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