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2-​Methoxyestradiol EIA Kit (strips)
Angiogenesis solid phase Photometr. Immunological Lysates, Fluids ELISAErklärungen der Abkürzungen ansehen. Cayman
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Cay582261-​480 480 st-wells

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2-​Methoxyestradiol (2-​ME2) is a natural metabolite of estradiol produced by CYP450-​dependant hydroxylation followed by catechol-​O-​methyltransferase-​catalyzed O-​methylation. Deficiency in catechol-​O-​methyltransferase is associated with pre-​eclampsia. Therefore, 2-​ME2 may be utilized as a plasma and urinary diagnostic marker for this disease, as well as a therapeutic supplement for its prevention. Several clinical trials have demonstrated the antitumor effects of 2-​ME2 in prostate cancer, breast cancer, renal cell carcinoma, ovarian cancer, glioblastoma, and multiple myeloma. Other studies indicate that 2-​ME2 exhibits more potent cardioprotective effects than estradiol. Cayman's 2-​Methoxyestradiol EIA Kit is a competitive assay that can be used for quantification of 2-​ME2 in plasma, urine, and other sample matrices.

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Kat #:
Cay582261-480
Menge:
480 st-wells

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Preis:
1.988 €

Schlagworte:
2-​Hydroxyestradiol 2-​methyl ester, 2-​ME2
Image Art 582261 Cayman 2-​Methoxyestradiol EIA Kit (strips)

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