2-Imino-4-methylpiperidine is a potent, general NOS inhibitor. It exhibits IC50 values of 0.1, 1.1, and 0.2 µM for inhibition of human iNOS, eNOS, and nNOS, respectively, at an arginine concentration of 30 µM.Formal Name: 3,4,5,6-tetrahydro-4-methyl-2-pyridinamine, acetate. CAS Number: 165383-72-2. Molecular...

AMT is a potent, relatively selective inhibitor of iNOS with a Ki of 4.2 nM in mouse macrophages. It inhibits other isoforms of NOS, but at higher concentrations, the IC50 values for rat nNOS and bovine eNOS are 34 and 150 nM, respectively.Formal Name: 5,6-dihydro-6-methyl-4H-1,3-thiazin-2-amine, hydrochloride. CAS...