2-Hydroxy Estradiol
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Larger quantity required? Request bulk
2-hydroxy Estradiol (2-HE2) is a cytochrome P450 metabolite of estradiol with low affinity for... more
Product information "2-Hydroxy Estradiol"
2-hydroxy Estradiol (2-HE2) is a cytochrome P450 metabolite of estradiol with low affinity for estrogen receptors. 2-HE is rapidly metabolized by catechol-O-methyltransferase (COMT) to form 2-methoxy estradiol (2-ME2) with a half-life of approximately ten minutes in rat. 2-ME2 has achieved considerable attention as an anti-cancer agent acting as an angiogenesis inhibitor via the HIF-1a pathway. Due to the rapid metabolism of 2-HE2, the effects attributed to 2-HE2, may actually be those of 2-ME2.
| Supplier: | LKT Laboratories |
| Supplier-Nr: | H9816 |
Properties
| Application: | Angiogenesis inhibitor |
| MW: | 288,38 D |
Database Information
| CAS : | 362-05-0| Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: +4°C) |
| Signal Word: | Warning |
| GHS Hazard Pictograms: |
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| H Phrases: | H351 |
| P Phrases: | P201, P202, P281, P308+P313, P405, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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