2'-Deoxyguanosine 5'-monophosphate (sodium salt hydrate)

2'-Deoxyguanosine 5'-monophosphate (dGMP) is used as a substrate of guanylate kinases to generate dGDP, which in turn is phosphorylated to dGTP, a nucleotide precursor used in DNA synthesis. In addition, dGMP can be efficiently phosphorylated by the type I thymidylate kinase of the malarial agent P. falciparum. In humans, deficiency of mitochondrial deoxyguanosine kinase, which synthesizes dGMP from ATP and deoxyguanosine, contributes to mitochondrial DNA depletion syndrome.Formal Name: 2'-deoxy-5'-guanylic acid, disodium salt hydrate. CAS Number: 146877-98-7. Synonyms: dGMP. Molecular Formula: C10H12N5O7P . 2Na [XH2O]. Formula Weight: 391.2. Purity: >95%. Formulation: (Request formulation change), A crystalline solid. Solubility: PBS (pH 7.2): 10 mg/ml. SMILES: O[C@H]1C[C@H](N2C=NC3=C2N=C(N)NC3=O)O[C@@H]1COP([O-])([O-])=O.[Na+].[Na+].O. InChi Code: InChI=1S/C10H14N5O7P.2Na.H2O/c11-10-13-8-7(9(17)14-10)12-3-15(8)6-1-4(16)5(22-6)2-21-23(18,19)20,,,/h3-6,16H,1-2H2,(H2,18,19,20)(H3,11,13,14,17),,,1H2/q,2*+1,/p-2/t4-,5+,6+,,,/m0.../s1. InChi Key: HQSJCEYJAGVPJG-BIHLCPNHSA-L.