- Search results for Cay10010460-1
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12 products were found matching "Cay10010460-1"!
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Item number: Cay10010469-10
ADHP is a highly sensitive, stable substrate for horseradish peroxidase (HRP) that enables selective detection of H2O2. This colorless, non-fluorescent reagent reacts with H2O2 to produce the fluorescent compound resorufin, which can be analyzed using an excitation wavelength of 520-550 nm and an emission wavelength...
Keywords: | A 6550, ADHP, Amplex Red(R), 1-(3,7-dihydroxy-10H-phenoxazin-10-yl)-ethanone |
Application: | HRP substrate |
CAS | 119171-73-2 |
MW: | 257.2 D |
From 34.00€
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Item number: Cay10010466-10
SP6000125 is a pan-inhibitor of JNK (IC50s = 0.04, 0.04, and 0.09 µM for JNK1, -2, and -3, respectively). It is greater than 300-fold selective for these enzymes over a panel of 17 additional kinases at 10 µM. SP6000125 reduces LPS-induced production of IL-1beta, IL-8, and TNF-alpha in isolated human peripheral...
Keywords: | 1PMV, NSC 75890, Pyrazolanthrone, anthra[1,9-cd]pyrazol-6(2H)-one |
Application: | JNK inhibitor |
CAS | 129-56-6 |
MW: | 220.2 D |
From 60.00€
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Item number: Cay10010401-96
Sirtuins (SIRTs) represent a distinct class of trichostatin A-insensitive lysyl-deacetylases (class III HDACs). Human SIRT1 is the homolog of yeast Silent information regulator 2 (Sir2) and has been shown to regulate the activity of the p53 tumor suppressor and inhibit apoptosis. Small molecule activators of SIRT1,...
Keywords: | SIRT1, hSIR2, hSIRT1, SIR2L1, EC=3.5.1.-, SIR2-like protein 1, NAD-dependent deacetylase sirtuin-1 |
Application: | SIRT1 inhibitor/activator screening |
Species reactivity: | human |
467.00€
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Item number: Cay10010468-10
15-Lipoxygenase inhibitor 1 is a 15-lipoxygenase (15-LO) inhibitor (IC50 = 18 µM). It scavenges DPPH (Cay-14805) radicals in a cell-free assay (IC50 = 69.6 µM).Formal Name: 4-methyl-2-(4-methylpiperazinyl)pyrimido[4,5-b]benzothiazine. CAS Number: 928853-86-5. Synonyms: 15-LO Inhibitor 1, 4-MMPB. Molecular Formula:...
Keywords: | 15-LO Inhibitor 1, 4-methyl-2-(4-methylpiperazinyl)pyrimido[4,5-b]benzothiazine |
Application: | 15-LO inhibitor |
CAS | 928853-86-5 |
MW: | 313.4 D |
From 43.00€
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Item number: Cay10010406-5
Fluprostenol is an F-series prostaglandin analog which has been approved for many years as a luteolytic in veterinary animals. The isopropyl ester of fluprostenol (travoprost) is an effective ocular hypotensive drug. Fluprostenol is the optically active enantiomer of fluprostenol and would be expected to have twice...
Keywords: | N-methyl-9alpha,11alpha,15R-trihydroxy-16-(3-(trifluoromethyl)phenoxy)-17,18,19,20-tetranor-prosta-5Z,13E-dien-1-amide |
Application: | Bioactive lipid assays |
MW: | 471.5 D |
From 94.00€
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Item number: Cay10010364-100
Fatty acid binding protein 5 (FABP5) is one of nine known cytosolic FABPs ranging in size from 14-15 kDa containing 127-132 amino acids. Members of this protein family exhibit high affinity for lipophilic ligands and were named according to the tissue from which they were initially isolated. FABP5 is found in skin,...
Keywords: | PA-FABP, PA-FABP, E-FABP {ECO:0000303|PubMed:8092987}, E-FABP {ECO:0000303|PubMed:8092987}, Fatty acid-binding protein,... |
Application: | WB |
MW: | 18 kD |
530.00€
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Item number: Cay10010564-100
Pyrimidine-4-carboxylic acid is a synthetic intermediate useful for pharmaceutical synthesis.Formal Name: 4-pyrimidinecarboxylic acid. CAS Number: 31462-59-6. Molecular Formula: C5H4N2O2. Formula Weight: 124.1. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 5 mg/ml,...
Keywords: | 4-pyrimidinecarboxylic acid |
Application: | Synthetic intermediate, pharmaceutical synthesis |
CAS | 31462-59-6 |
MW: | 124.1 D |
From 28.00€
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Item number: Cay10010064-10
15(S)-15-methyl Prostaglandin F2alpha has been shown to have potent uterine stimulant and abortifacient properties when administered intramuscularly to induce labor. 15(S)-15-methyl PGF2alpha ethyl amide is a lipophilic analog of 15(S)-15-methyl PGF2alpha methyl ester. Prostaglandin esters are generally hydrolyzed...
Keywords: | 15(S)-15-methyl PGF2alpha ethyl amide, 9alpha,11alpha,15S-trihydroxy-15-methyl-prosta-5Z,13E-dien-1-oic acid, ethyl amide |
Application: | Lipophilic 15(S)-15-methyl PGF2alpha methyl ester analog |
MW: | 395.6 D |
From 117.00€
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Item number: Cay10010410-1
Four G protein-coupled receptors, EP1-4, initiate cellular signaling in response to prostaglandin PGE2. The receptor EP1 acts via Galphaq to evoke diverse effects, including renal vasoconstriction, bronchoconstriction, hyperalgesia, allodynia, gastric protection, hyperthermia, and sleep inhibition. GW 848687X is a...
Keywords: | 6-[2-[5-chloro-2-[(2,4-digluorophenyl)methoxy]phenyl]-1-cyclopenten-1-yl]-2-pyridinecarboxylic acid |
Application: | EP1 receptor antagonist |
CAS | 612831-24-0 |
MW: | 441.9 D |
From 119.00€
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Item number: Cay10010426-10
KRP 203 is a sphingosine-1-phosphate receptor 1 (S1P1) agonist. It selectively induces calcium mobilization in CHO-K1 cells expressing mouse S1P1 over mouse S1P3 and S1P4 (EC50s = 0.84, >1,000, and 9.61 nM, respectively). In vivo, KRP 203 (0.3 mg/kg) prevents the development of wasting syndrome, decreases diarrhea...
Keywords: | Mocravimod (hydrochloride), 2-amino-2-[2-[2-chloro-4-[[3-(phenylmethoxy)phenyl]thio]phenyl]ethyl]-1,3-propanediol,... |
Application: | S1P1 receptor agonist |
CAS | 509088-69-1 |
MW: | 480.4 D |
From 68.00€
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Item number: Cay10010246-10
Glycogen synthase kinase 3 (GSK3) is a serine/threonine protein kinase that is inhibited by an assortment of extracellular stimuli including insulin, growth factors, cell specification factors, and cell adhesion. SB-216763 is a potent and selective cell permeable ATP-competitive inhibitor of GSK3alpha with an IC50...
Keywords: | 3-(2,4-dichlorophenyl)-4-(1-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione |
Application: | GSK inhibitor |
CAS | 280744-09-4 |
MW: | 371.2 D |
From 98.00€
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Item number: Cay10010164-10
1-Oleyl-2-hydroxy-sn-glycero-3-PA (1-octadecyl LPA) is a LPA analog containing stearic acid at the sn-1 position. LPA binds to one of five different G protein linked receptors to mediate a variety of biological responses including cell proliferation, smooth muscle contraction, platelet aggregation, neurite...
Keywords: | 1-Octadecyl LPA, 3-(octadecyloxy)-1-(dihydrogen phosphate)-1,2-propanediol |
Application: | Bioactive lipid assays |
CAS | 52977-29-4 |
MW: | 424.6 D |
From 35.00€
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