2 products were found matching "Cay11039-100"!

No results were found for the filter!
FR122047 (hydrochloride)
FR122047 (hydrochloride)

Item number: Cay10039-10

FR122047 is a selective inhibitor of COX-1. The IC50 values for inhibition of human COX-1 and COX-2 are 0.028 and 65 µM, respectively. In human platelet-rich plasma, FR122047 inhibits arachidonic acid, collagen, and ADP-induced platelet aggregation with an IC50 of 180-200 nM, which is nearly 100 times more potent...
Keywords: 1-[[4,5-bis(4-methoxyphenyl)-2-thiazolyl]carbonyl]-4-methyl-piperazine, monohydrochloride
Application: COX-1 inhibitor
CAS 130717-51-0
MW: 460 D
From 43.00€ *
Review
17-AAG
17-AAG

Item number: Cay11039-10

17-AAG is an inhibitor of heat shock protein 90 (Hsp90) and a derivative of geldanamycin (Cay-13355) that selectively inhibits BT474 tumor cell Hsp90 over fibroblast Hsp90 (IC50s = 5 and 943 nM, respectively). It inhibits the growth of prostate cancer cell lines (IC50s = 25-45 nM) and promotes the degradation of...
Keywords: BMS 722782, CP 127374, KOS 953, NSC 330507, Tanespimycin, 17-demethoxy-17-(2-propenylamino)-geldanamycin
Application: Hsp90 inhibitor
CAS 75747-14-7
MW: 585.7 D
From 50.00€ *
Review