3 products were found matching "Cay11039"!

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17-AAG
17-AAG

Item number: Cay11039-1

17-AAG is an inhibitor of heat shock protein 90 (Hsp90) and a derivative of geldanamycin (Cay-13355) that selectively inhibits BT474 tumor cell Hsp90 over fibroblast Hsp90 (IC50s = 5 and 943 nM, respectively). It inhibits the growth of prostate cancer cell lines (IC50s = 25-45 nM) and promotes the degradation of...
Keywords: BMS 722782, CP 127374, KOS 953, NSC 330507, Tanespimycin, 17-demethoxy-17-(2-propenylamino)-geldanamycin
Application: Hsp90 inhibitor
CAS 75747-14-7
MW: 585.7 D
From 50.00€ *
Review
FR122047 (hydrochloride)
FR122047 (hydrochloride)

Item number: Cay10039-5

FR122047 is a selective inhibitor of COX-1. The IC50 values for inhibition of human COX-1 and COX-2 are 0.028 and 65 µM, respectively. In human platelet-rich plasma, FR122047 inhibits arachidonic acid, collagen, and ADP-induced platelet aggregation with an IC50 of 180-200 nM, which is nearly 100 times more potent...
Keywords: 1-[[4,5-bis(4-methoxyphenyl)-2-thiazolyl]carbonyl]-4-methyl-piperazine, monohydrochloride
Application: COX-1 inhibitor
CAS 130717-51-0
MW: 460 D
From 43.00€ *
Review
Anti-CD25/Interleukin-2Ralpha Monoclonal Antibody (PE) (Clone 143-13)
Anti-CD25/Interleukin-2Ralpha Monoclonal Antibody (PE)...

Item number: Cay10339-1

CD25, also known as interleukin-2 receptor alpha (IL-2Ralpha), is a transmembrane glycoprotein. It is composed of two domains, D1 and D2, and associates with the CD122/IL-2beta and CD132/IL-2gammac subunits to form the heterotrimeric IL-2 receptor. CD25 is expressed in activated T and B cells, regulatory T cells,...
Keywords: Anti-p55, Anti-p55, Anti-CD25, Anti-CD25, Anti-IL2RA, Anti-IL2-RA, Anti-IL2-RA, Anti-IL-2-RA, Anti-IL-2-RA, Anti-TAC...
Application: FC, ICC, IHC (frozen)
Host: Mouse
Species reactivity: human
472.00€ *
Review