13 products were found matching "Cay36720-0.1"!

Sulfadoxin-d4 is intended for use as an internal standard for the quantification of sulfadoxin (Cay-21488) by GC- or LC-MS. Sulfadoxin is a sulfonamide antibiotic that inhibits dihydropteroate synthetase (DHPS), an enzyme involved in folic acid (Cay-20515) synthesis. Sulfadoxin competes with 4-aminobenzoate (PABA),...

Clinodiside A is a triterpenoid saponin that has been found in Clinopodium.Formal Name:...

BI-1467335 is an inhibitor of vascular adhesion protein-1 (VAP-1, IC50 = 50s = >1,000 and >10,000 nM, respectively). Oral administration of BI-1467335 (10 mg/kg per day) reduces plasma total cholesterol, LDL, and glucose levels, as well as decreases the recruitment of macrophages to atherosclerotic lesions and the...

Nimodipine-d7 is intended for use as an internal standard for the quantification of nimodipine (Cay-14573) by GC- or LC-MS. Nimodipine is an inhibitor of L-type voltage-gated calcium (Cav) channels. It is selective for Cav1.2 over Cav1.3 channels (IC50s = 0.139 and 2.7 µM, respectively), as well as R-, N-, and...

Sildenafil chlorosulfonyl is a synthetic intermediate in the synthesis of the phosphodiesterase 5 (PDE5) inhibitor sildenafil (Cay-10008671). It is also a potential impurity found in commercial preparations of sildenafil.Formal Name:...

5-Aminofluorescein is a fluorescent compound and an inhibitor of the mRNA N6-methyladenosine (m6A) demethylase fat mass and obesity-associated (FTO) protein (IC50 = 6.55 µM). It displays excitation/emission maxima of 490 and 515 nm, respectively, and has been conjugated to human serum albumin for fluorescence...

Chamazulene is a terpene that has been found in chamomile (M. recutita) flowers and has anti-inflammatory and antioxidant activities. It reduces increases in matrix metalloproteinase-3 (MMP-3), MMP-9, COX-2, inducible nitric oxide synthase (iNOS), and p65 NF-kappaB levels in IL-1beta-stimulated primary rat...

Cycleanine is an alkaloid that has been found in T. subcordata and has anticancer and antimalarial activities. It selectively inhibits the growth of OVCAR-8, A2780, IGROV-1, and OVCAR-4 ovarian cancer cells (IC50s = 10, 7.6, 14, and 7.2 µM, respectively) over non-cancerous ovarian surface epithelial cells (IC50 = 35...

Granzyme B is a serine protease that is involved in cytotoxic T lymphocyte- and natural killer cell-induced cell death. It localizes to cytoplasmic granules prior to release into the immunological synapse formed with a target cell. Granzyme B cleaves its substrates after an aspartate residue and targets caspase-3,...

Goralatide is a tetrapeptide regulator of hematopoiesis. It decreases the proportion of mouse high proliferative potential colony forming cells (HPP-CFCs) in S phase when cultured using regenerating femoral marrow conditioned medium at a concentration of 1 ng/ml. Goralatide (4 µg/kg twice per day) reduces decreases...

Epidermal growth factor receptor (EGFR), also known as HER1 and ErbB1, is a cell surface receptor and member of the EGF family of receptor tyrosine kinases with roles in cell proliferation, differentiation, and survival. It is a 170 kDa transmembrane receptor composed of an intracellular tyrosine kinase domain, a...

(±)-CBCH (Cay-36702) is an analytical reference standard that is structurally similar to known phytocannabinoids. This product is intended for research and forensic applications.Formal Name: 7-hexyl-2-methyl-2-(4-methylpent-3-en-1-yl)-2H-chromen-5-ol. Molecular Formula: C22H32O2. Formula Weight: 328.5. Purity: >98%....