13 products were found matching "Cay37720-0.1"!

Sulfadoxin-d4 is intended for use as an internal standard for the quantification of sulfadoxin (Cay-21488) by GC- or LC-MS. Sulfadoxin is a sulfonamide antibiotic that inhibits dihydropteroate synthetase (DHPS), an enzyme involved in folic acid (Cay-20515) synthesis. Sulfadoxin competes with 4-aminobenzoate (PABA),...

Granzyme B is a serine protease that is involved in cytotoxic T lymphocyte- and natural killer cell-induced cell death. It localizes to cytoplasmic granules prior to release into the immunological synapse formed with a target cell. Granzyme B cleaves its substrates after an aspartate residue and targets caspase-3,...

TNF-alpha is a cytokine and a member of the TNF/TNF receptor (TNFR) cytokine superfamily. TNF-alpha is produced as a 233-amino acid transmembrane precursor protein from which mature, soluble TNF-alpha is formed by proteolysis. Soluble TNF-alpha is a 157-amino acid polypeptide, cleaved from the precursor protein on...

Epidermal growth factor receptor (EGFR), also known as HER1 and ErbB1, is a cell surface receptor and member of the EGF family of receptor tyrosine kinases with roles in cell proliferation, differentiation, and survival. It is a 170 kDa transmembrane receptor composed of an intracellular tyrosine kinase domain, a...

1-Stearoyl-2-eicosapentaenoyl-sn-glycero-3-PE is a phospholipid that contains stearic acid (Cay-10011298) and eicosapentaenoic acid (EPA, Cay-90110, Cay-90110.1, Cay-21908) at the sn-1 and sn-2 positions, respectively. It has been found in fish oils.Formal Name: 5Z,8Z,11Z,14Z,17Z-eicosapentaenoic acid,...

Thioredoxin 1 (Trx1) is a thiol-disulfide oxidoreductase and part of the antioxidant thioredoxin system that is involved in the maintenance of cellular thiol redox homeostasis. It is ubiquitously expressed, localizes primarily to the cytoplasm with some nuclear localization, and is upregulated in and released from...

Nimodipine-d7 is intended for use as an internal standard for the quantification of nimodipine (Cay-14573) by GC- or LC-MS. Nimodipine is an inhibitor of L-type voltage-gated calcium (Cav) channels. It is selective for Cav1.2 over Cav1.3 channels (IC50s = 0.139 and 2.7 µM, respectively), as well as R-, N-, and...

306-N16B is an ionizable cationic lipid. It has been used in the generation of lipid nanoparticles (LNPs). Intravenous administration of LNPs containing 306-N16B and encapsulating an mRNA reporter accumulate specifically in the mouse lung primarily in lung endothelial cells. LNPs containing both 306-N16B and...

Ractopamine-d3 is intended for use as an internal standard for the quantification of ractopamine (Cay-27613) by GC- or LC-MS. Ractopamine is a trace amine-associated receptor 1 (TAAR1) agonist. It increases chloride conductance in X. laevis oocytes expressing the human cystic fibrosis transmembrane conductance...

Dicloxacillin is a semisynthetic penicillin antibiotic that has activity against Gram-positive bacteria (MICs = 0.02-0.24 µg/ml for S. pyogenes, S. aureus, and D. pneumoniae). Dicloxacillin is protective against S. pyogenes, S. aureus, and D. pneumoniae infections in mice when administered subcutaneously or orally...

MK-571 is a cysteinyl leukotriene 1 (CysLT1) receptor antagonist (Ki = 2.1 nM in a radioligand binding assay using isolated human lung membranes). It inhibits contractions induced by leukotriene D4 (LTD4, Cay-20310) or LTE4 (Cay-20410) in histamine-primed isolated guinea pig trachea (pA2s = 9.4 and 9.1,...

TNF-alpha is a cytokine and member of the TNF/TNF receptor (TNFR) cytokine superfamily. TNF-alpha is produced as a 233-amino acid transmembrane precursor protein from which mature, soluble TNF-alpha is formed by proteolysis. Soluble TNF-alpha is a 157-amino acid polypeptide, cleaved from the precursor protein on the...