20 products were found matching "Cay34710-0.1"!

N-Methylcytisine is an alkaloid that has been found in L. albus and has diverse biological activities. It is an agonist of nicotinic acetylcholine receptors (nAChRs) and selectively binds to nAChRs over muscarinic acetylcholine receptors (mAChRs, IC50s = 0.05 and 417 µM, respectively). It elicits whole-cell currents...

Cyclo(Phe-Pro) is a bacterial quorum-sensing molecule that has been found in V. cholerae. It enhances ToxR-dependent transcription of leuO, a DNA binding protein, and inhibits virulence factor production in V. cholerae. Cyclo(Phe-Pro) is an inhibitor of the interaction between retinoic acid-inducible gene I (RIG-I)...

Antimycin A complex is a bacterial metabolite complex that has been found in Streptomyces and is composed of the major components antimycin A1 (Cay-19433), -A2 (Cay-21997), -A3 (Cay-21998), and -A4 (Cay-21999), as well as minor components, including antimycin A5 and -A6, among others. It induces the synthesis of...

Lithospermoside is a nitrile glucoside that has been found in Cowania mexicana and has antitumor activity. It inhibits activation of Epstein-Barr virus early antigen (EBV-EA) induced by phorbol 12-myristate 13-acetate (TPA, Cay-10008014), a marker of tumor formation, in Raji cells.Formal Name:...

Catechol is a polyphenol that has been found in a variety of natural and anthropogenic sources. It has been found in teas, fruits, and vegetables, as well as cigarette smoke, and is used in rubber and plastic production. Catechol is also used as a precursor in the synthesis of organic polymerization inhibitors,...

ALC-0315 is an ionizable cationic amino lipid that has been used in combination with other lipids in the formation of lipid nanoparticles (LNPs). Administration of severe acute respiratory coronavirus 2 (SARS-CoV-2) mRNA in ALC-0315-containing LNPs induces the production of IgG that binds to the SARS-CoV-2...

L-Leu-AMC is a fluorogenic substrate for leucine aminopeptidase. Upon enzymatic cleavage by leucine aminopeptidase, AMC is released and its fluorescence can be used to quantify leucine aminopeptidase activity. AMC displays excitation/emission maxima of 340-360/440-460 nm, respectively.Formal Name:...

N-Propionylglycine is a glycine-conjugated form of propionic acid. It is produced by glycine-N-acylase from propionyl-CoA, a catabolic intermediate that accumulates when the activity of propionyl-CoA carboxylase, the enzyme that converts propionyl-CoA to methylmalonyl-CoA, is deficient, in the mitochondria. Urinary...

Benzetimide is a muscarinic acetylcholine receptor (mAChR) antagonist. It induces mydriasis and inhibits pilocarpine-induced salivation and lacrimation in rats (ED50s = 0.06 and 0.04 mg/kg, respectively).Formal Name: 3-phenyl-1'-(phenylmethyl)-[3,4'-bipiperidine]-2,6-dione, monohydrochloride. CAS Number: 5633-14-7....

Orcinol is a polyketide synthase-derived phenol that has been found in F. graminearum and has diverse biological activities. It scavenges DPPH (Cay-14805) radicals (IC50 = 2.93 mM). Orcinol (2.5 and 5 mg/kg) increases the number of entries into and percentage of time spent in the open arms of the elevated plus maze...

Pendimethalin is a dinitroaniline herbicide. It controls johnsongrass and increases seed cotton yield when used at concentrations ranging from 0.56 to 1.12 kg/ha. Pendimethalin (25-500 µM) induces the production of reactive oxygen species (ROS) and genotoxicity in isolated human peripheral lymphocytes. In vivo,...

7-ethyl Camptothecin is a derivative of camptothecin (Cay-11694) and an anticancer agent. It inhibits wild-type but not Gly533 mutant topoisomerase I in RPMI-8402 and CPT-K5 cells, respectively (IC50s = 5.48 and >2,500 nM, respectively). 7-ethyl Camptothecin is cytotoxic to ADJ/PC6 SN-38-sensitive and PC6/SN2-5H2...