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Item number: Cay81520-5

1400W is a potent, selective inhibitor of iNOS. Using purified human iNOS, nNOS, and eNOS, 1400W exhibits Ki values of 7 nM, 2 µM, and 50 µM, respectively. In rat aortic rings it is at least 1,000-fold more potent against iNOS compared to eNOS. In mice bearing a murine mammary carcinoma, continuous infusion of 1400W...

Keywords:	N-[[3-(aminomethyl)phenyl]methyl]-ethanimidamide, dihydrochloride
Application:	iNOS inhibitor
CAS	214358-33-5
MW:	250.2 D

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