- Search results for Cay81510
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7 products were found matching "Cay81510"!
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Item number: Cay81510-500
1,4-PBIT is a potent inhibitor of purified human iNOS and nNOS with Ki values of 7.4 and 16 nM, respectively, compared to a Ki of 360 nM for human eNOS. Its inhibition in whole cells is greatly diminished, presumably to poor membrane permeability.Formal Name: S,S'-1,4-phenylene-bis(1,2-ethanediyl)bis-isothiourea,...
Keywords: | S,S'-1,4-phenylene-bis(1,2-ethanediyl)bis-isothiourea, dihydrobromide |
Application: | iNOS inhibitor, nNOS inhibitor |
CAS | 157254-60-9 |
MW: | 444.2 D |
From 23.00€
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Item number: Cay81540-10
Carboxy-PTIO is a NO scavenger. It reacts stoichiometrically with NO and can be used for EPR detection of NO.Formal Name: 2-(4-carboxyphenyl)-4,5-dihydro-4,4,5,5-tetramethyl-1H-imidazolyl-1-oxy-3-oxide, monopotassium salt. CAS Number: 148819-94-7. Molecular Formula: C14H16N2O4 . K. Formula Weight: 315.4. Purity:...
Keywords: | 2-(4-carboxyphenyl)-4,5-dihydro-4,4,5,5-tetramethyl-1H-imidazolyl-1-oxy-3-oxide, monopotassium salt |
Application: | NO scavenger |
CAS | 148819-94-7 |
MW: | 315.4 D |
From 50.00€
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Item number: Cay81560-10
YC-1 is an nitric oxide (NO)-independent activator of soluble guanylyl cyclase. It inhibits collagen (10 µg/ml) and thrombin (0.1 U/ml) induced platelet aggregation with IC50 values of 11.7-14.6 and 57.3-59.3 µM, respectively. In the absence of NO or carbon monoxide (CO), 200 µM YC-1 increases the activity of...
Keywords: | 5-[1-(phenylmethyl)-1H-indazol-3-yl]-2-furanmethanol |
Application: | Platelet aggregation inhibitor |
CAS | 170632-47-0 |
MW: | 304.3 D |
From 24.00€
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Item number: Cay81530-10
Aminoguanidine is equipotent to L-NMMA and L-NNA as an inhibitor of iNOS. The IC50 values for inhibition of mouse iNOS and rat nNOS are 5.4 and 160 µM, respectively. Aminoguanidine also inhibits induction of iNOS protein expression by endotoxin in rat macrophages.Formal Name: hydrazinecarboximidamide,...
Keywords: | Aminoguanidinium chloride, GER 11, Pimagedine, hydrazinecarboximidamide, monohydrochloride |
Application: | iNOS inhibitor |
CAS | 1937-19-5 |
MW: | 110.5 D |
From 34.00€
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Item number: Cay81520-10
1400W is a potent, selective inhibitor of iNOS. Using purified human iNOS, nNOS, and eNOS, 1400W exhibits Ki values of 7 nM, 2 µM, and 50 µM, respectively. In rat aortic rings it is at least 1,000-fold more potent against iNOS compared to eNOS. In mice bearing a murine mammary carcinoma, continuous infusion of 1400W...
Keywords: | N-[[3-(aminomethyl)phenyl]methyl]-ethanimidamide, dihydrochloride |
Application: | iNOS inhibitor |
CAS | 214358-33-5 |
MW: | 250.2 D |
From 73.00€
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Item number: Cay81590-10
Staurosporine (Stsp) is potent inhibitor of protein kinase C (PKC) from rat brain, exhibiting an IC50 value of 2.7 nM. It inhibits rat recombinant PKC-alpha approximately 100- and 1,000-fold better than PKC-delta and PKC-zeta, respectively. However, Stsp is non-selective in that it also inhibits the activity of a...
Keywords: | Stsp,... |
Application: | PKC inhibitor |
CAS | 62996-74-1 |
MW: | 466.5 D |
From 43.00€
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Item number: Cay81500-10
1,3-PBIT is a potent inhibitor of iNOS with a Ki of 47 nM compared to Ki values for eNOS and nNOS are 9 and 0.25 µM, respectively, for the purified human enzymes. Its inhibition in whole cells is greatly diminished, presumably to poor membrane permeability.Formal Name:...
Keywords: | S,S'-1,3-phenylene-bis(1,2-ethanediyl)bis-isothiourea, dihydrobromide |
Application: | iNOS inhibitor |
CAS | 200716-66-1 |
MW: | 444.2 D |
From 26.00€
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