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1,3-PBIT (dihydrobromide)
1,3-PBIT (dihydrobromide)

Item number: Cay81500-50

1,3-PBIT is a potent inhibitor of iNOS with a Ki of 47 nM compared to Ki values for eNOS and nNOS are 9 and 0.25 µM, respectively, for the purified human enzymes. Its inhibition in whole cells is greatly diminished, presumably to poor membrane permeability.Formal Name:...
Keywords: S,S'-1,3-phenylene-bis(1,2-ethanediyl)bis-isothiourea, dihydrobromide
Application: iNOS inhibitor
CAS 200716-66-1
MW: 444.2 D
From 26.00€ *
Review
Aminoguanidine (hydrochloride)
Aminoguanidine (hydrochloride)

Item number: Cay81530-100

Aminoguanidine is equipotent to L-NMMA and L-NNA as an inhibitor of iNOS. The IC50 values for inhibition of mouse iNOS and rat nNOS are 5.4 and 160 µM, respectively. Aminoguanidine also inhibits induction of iNOS protein expression by endotoxin in rat macrophages.Formal Name: hydrazinecarboximidamide,...
Keywords: Aminoguanidinium chloride, GER 11, Pimagedine, hydrazinecarboximidamide, monohydrochloride
Application: iNOS inhibitor
CAS 1937-19-5
MW: 110.5 D
From 34.00€ *
Review
1,4-PBIT (dihydrobromide)
1,4-PBIT (dihydrobromide)

Item number: Cay81510-500

1,4-PBIT is a potent inhibitor of purified human iNOS and nNOS with Ki values of 7.4 and 16 nM, respectively, compared to a Ki of 360 nM for human eNOS. Its inhibition in whole cells is greatly diminished, presumably to poor membrane permeability.Formal Name: S,S'-1,4-phenylene-bis(1,2-ethanediyl)bis-isothiourea,...
Keywords: S,S'-1,4-phenylene-bis(1,2-ethanediyl)bis-isothiourea, dihydrobromide
Application: iNOS inhibitor, nNOS inhibitor
CAS 157254-60-9
MW: 444.2 D
From 23.00€ *
Review