111 products were found matching "LKT-G9648.100"!

Lomustine posseses antitumor activity similar to carmustine

Gambogic acid is a xanthonoid isolated from the brownish or orange resin from Garcinia hanburyi. Its anticancer activities are due to apoptosis induction, inhibition of topoisomerase and telomerase, and angiogenesis modification.

Smo inhibitor.

A nontoxic, natural compound. One of its derivatives 1,4-GL increases detoxification of carcinogens and tumor promoters/ progressors by inhibiting beta-glucuronidase and preventing hydrolysis of their glucuronides. When it was fed during the initiation , promotion, or both phases of chemically induced rat mammary...

Endogenous neurotransmitter, GABA agonist.

DAT inhibitor.

A natural product isolated from parsley oil. An inducer of glutathione S-transferase enzymes and inhibitor of chemical carcinogenesis.

An ADP receptor antagonist that inhibits platelet aggregation.

Is an experimental anticancer drug that is activated to a toxic radical only at very low levels of oxygen (hypoxia). Such levels are common in human solid tumors, a phenomenon known as tumor hypoxia.

White crystalline solid. A natural product isolated from the traditional Chinese antimalarial herb Atremisia annua. It has shown cytotoxic properties against several tumor cell lines, including Ehrlich ascites carcinoma cells.

Brevetoxins are lipid-soluble polyether neurotoxins produced by the dinoflagellate Karenia brevis. Brevetoxins act as agonists, binding the neurotoxin site 5 on SCN4A/Nav1.4 and SCN5A/Nav1.5 voltage-gated Na+ channels in skeletal muscle and cardiac tissue, producing a channel opening effect, this activity results in...