12-Lipoxygenase (platelet-type, mouse recombinant)

12-Lipoxygenase (platelet-type, mouse recombinant)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay10341-25 25 µg -

6 - 10 business days*

489.00€
 
12-Lipoxygenase (12-LO) catalyzes the formation of 12-HpETE from arachidonic acid. There are two... more
Product information "12-Lipoxygenase (platelet-type, mouse recombinant)"
12-Lipoxygenase (12-LO) catalyzes the formation of 12-HpETE from arachidonic acid. There are two main types of 12-LO, platelet-type and leukocyte-type, which share only 60% identity at the amino acid level and strongly differ in substrate specificity and enzyme kinetics. Leukocyte-type 12-LO has the ability to also produce 15-HpETE, however, platelet-type predominately forms 12-HpETE. Epidermal-type 12(S)- and 12(R)-LO enzymes have also been characterized, which catalyze the synthesis of their respective stereospecific 12-HETE products.Synonyms: Arachidonate 12-Lipoxygenase, 12-LO, 12-LOX. Purity: >80% estimated by SDS-PAGE. Source: Active recombinant mouse C-terminal His-tagged protein expressed in insect cells. MW: 76 kDa. Formulation: (Request formulation change), 50 mM sodium phosphate pH 7.2, 100 mM sodium chloride, 20 µM FeCl2, and 30% glycerol. UniProt Accession #: P39655.
Keywords: Alox12, P-12LO, P-12LO, Alox12p, 12S-LOX, 12S-LOX, 12S-lipoxygenase, 12S-lipoxygenase, Lipoxin synthase 12-LO, Lipoxin synthase 12-LO, Linoleate (13S)-lipoxygenase, Linoleate (13S)-lipoxygenase, Platelet-type lipoxygenase 12, Platelet-type lipoxygenase 12
Supplier: Cayman Chemical
Supplier-Nr: 10341

Properties

Application: Enzyme activity
Conjugate: No
MW: 76,4 kD
Purity: >80% estimated by SDS-PAGE

Handling & Safety

Storage: -80°C
Shipping: -80°C (International: -80°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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