12 products were found matching "Cay10341-10"!

Steviol is the aglycon derivative of steviol glycosides, which are natural sweeteners isolated from S. rebaudiana. Steviol inhibits human organic anion transporters (hOATs) in uptake assays using murine cells from the S2 segment of proximal tubules. It is selective for hOAT1 and hOAT3 over hOAT2 and hOAT4 (IC50s =...

N-Acylated ethanolamines (NAE) are naturally-occurring lipids that have diverse bioactivities. The different types of NAE can be derived from glycerophospho-linked precursors by the activity of glycerophosphodiesterase 1 (GDE1). Glycerophospho-N-arachidonoyl ethanolamine is the precursor of arachidonoyl ethanolamide...

Dimebolin is a neuroprotective agent. It binds to histamine H1 and H2 receptors (IC50s = 3.8 and 287 nM, respectively), as well as alpha1A-, alpha1B-, alpha1D-, and alpha2A-adrenergic receptors (ARs), imidazoline I2 receptors, and the serotonin (5-HT) receptor subtypes 5-HT2A, 5-HT2C, 5-HT6, and 5-HT7 (Kis = 8-313...

Cyclooxygenase metabolism of EPA to produce Prostaglandin E3 (PGE3) has been reported in biosynthetic preparations of ovine seminal vesicles and in the ocular tissues of primates. Prostaglandin A3 (PGA3) is an expected non-enzymatic dehydration product of this PGE3. PGA3 exhibits good affinity for the canine EP2 and...

PDM 11 is a derivative of the antioxidant trans-resveratrol that is inactive in vitro in assays of resveratrol activity. It does not activate quinone reductase 1, inhibit quinone reductase 2, or affect nitric oxide production or quenching of free radicals. It does not interact with estrogen receptors or affect the...

12-Lipoxygenase (12-LO) catalyzes the formation of 12-HpETE from arachidonic acid. There are two main types of 12-LO, platelet-type and leukocyte-type, which share only 60% identity at the amino acid level and strongly differ in substrate specificity and enzyme kinetics. Leukocyte-type 12-LO has the ability to also...

6-MAPB (hydrochloride) (Cay-14110) is an analytical reference standard categorized as a benzofuran. This product is intended for research and forensic applications.Formal Name: N,alpha-dimethyl-6-benzofuranethanamine, monohydrochloride. CAS Number: 2731011-08-6. Molecular Formula: C12H15NO . HCl. Formula Weight:...

2-Arachidonoyl glycerol (2-AG, Cay-62160) has been isolated from porcine brain, and has been characterized as the natural endocannabinoid ligand for the CB1 receptor. Incubation of 2-AG with cyclooxygenase-2 and specific prostaglandin H2 (PGH2) isomerases in cell cultures and isolated enzyme preparations results in...

Docosapentaenoic acid-d5 methyl ester is intended for use as an internal standard for the quantification of docosapentaenoic acid methyl ester (Cay-9001870) by GC- or LC-MS. Docosapentaenoic acid methyl ester is an esterified form of docosapentaenoic acid (Cay-90165, Cay-21907). It has been used as a reference...

19-Norandrostenedione (Cay-34110) is an analytical reference standard categorized as an anabolic androgenic steroid. 19-Norandrostenedione is a precursor in the biosynthesis of nandrolone (Cay-21173). 19-Norandrostenedione is regulated as a Schedule III compound in the United States. This product is intended for...

N-Desmethylclomipramine (hydrochloride) (Cay-19034) is an analytical reference material that is an active metabolite of clomipramine. This product is intended for research and forensic applications.Formal Name: 3-chloro-10,11-dihydro-N-methyl-5H-dibenz[b,f]azepine-5-propanamine, monohydrochloride. CAS Number:...

Forsythoside A is a phenylethanoid glycoside that has been found in F. suspensa and has diverse biological activities. It is active against E. coli, P. aeruginosa, and S. aureus (MICs = 38.33, 38.33, and 76.67 µg/ml, respectively). Forsythoside A scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH, Cay-14805) radicals...