15 products were found matching "Cay34550-0.1"!

Caudatin is a C-21 steroid that has been found in C. auriculatum and has anticancer activity. It is cytotoxic to SMMC-7721, MCF-7, and HeLa cells (IC50s = 24.95, 65.82, and 247.54 µM, respectively). Caudatin (50-300 µM) induces apoptosis in and inhibits mammosphere formation by MDA-MB-231 breast cancer cells, as...

Picosulfate is a stimulant laxative and prodrug form of desacetyl bisacodyl (DAB, Cay-20928). Unlike bisacodyl (Cay-28826), picosulfate is hydrolyzed to DAB by colonic microbiota. Picosulfate (5 mg/kg) increases excreted fecal weight in a rat model of loperamide-induced constipation. Formulations containing...

Kanamycin B is an aminoglycoside antibiotic. It is active against S. aureus, E. coli, P. aeruginosa, and P. rettgeri (MICs = 0.78-25 µg/ml). Kanamycin B binds to the ribosomal decoding A site to interfere with bacterial protein synthesis.Formal Name:...

Pendimethalin is a dinitroaniline herbicide. It controls johnsongrass and increases seed cotton yield when used at concentrations ranging from 0.56 to 1.12 kg/ha. Pendimethalin (25-500 µM) induces the production of reactive oxygen species (ROS) and genotoxicity in isolated human peripheral lymphocytes. In vivo,...

Naptalam is an auxin inhibitor and herbicide. It reduces coleoptile accumulation of the polar auxin indole-3-acetic acid (Cay-16954) in maize when used at a concentration of 50 µM. Naptalam inhibits various auxin-dependent processes, such as embryo development, lateral root development, leaf vein patterning, apical...

Kaempferol 3-glucuronide is a flavonol glycoside that has been found in Fragaria and an active metabolite of kaempferol (Cay-11852) that has diverse biological activities. It is formed from kaempferol primarily in the small intestine. Kaempferol 3-glucuronide (0.1, 1, and 10 µM) induces Akt activity in mouse liver...

Glycine-d5 is intended for use as an internal standard for the quantification of glycine by GC- or LC-MS. Glycine is a conditionally essential amino acid and the major inhibitory neurotransmitter in the spinal cord and brainstem. It is synthesized from threonine, choline, hydroxyproline, and serine via interorgan...

DiFMUP is a fluorogenic substrate for phosphatases. Upon enzymatic cleavage by phosphatases, 6,8-difluoro-7-hydroxy-4-methylcoumarin (Cay-36017) is released, which has an absorption/emission maxima of 358/455 nm, respectively, and its fluorescence can be used to quantify phosphatase activity. DiFMUP has been used to...

GS-621763 is an orally bioavailable prodrug form of the antiviral nucleotide analog GS-443902, which is also an active metabolite of remdesivir (Cay-30354). Upon intestinal absorption, GS-621763 is metabolized into the intermediate metabolite GS-441524 (Cay-30469), which is then further metabolized to the active...

Faropenem is a broad-spectrum penem antibiotic. It is active against a panel of 12 Gram-positive (MIC50s = 0.008-1 mg/L) and 15 Gram-negative (MIC50s = 0.06-16 mg/L) bacteria. Faropenem (20 mg/kg) reduces the number of lung colony forming units (CFUs) in a mouse model of H. influenzae-induced respiratory tract...

IPG-1 AM is a cell-permeable fluorescent potassium indicator. It binds to potassium (Kd = 50 mM) and displays excitation/emission maxima of 525/545 nm, respectively. IPG-1 AM is also available in a cell-impermeable form (Cay-35543).Formal Name:...

IPG-1 TMA is a cell-impermeable fluorescent potassium indicator. It binds to potassium (Kd = 50 mM) and displays excitation/emission maxima of 525/545 nm, respectively, and can be used in lipid membrane-free systems or liposomes or can be introduced into cells by electroporation, microinjection, or other methods....