1-Palmitoyl-2-hydroxy-sn-glycero-3-PA

1-Palmitoyl-2-hydroxy-sn-glycero-3-PA (1-Palmitoyl LPA) is a LPA analog containing palmitic acid at the sn-1 position. LPA binds to one of at least five different G protein-coupled receptors to mediate a variety of biological responses including cell proliferation, smooth muscle contraction, platelet aggregation, neurite retraction, and cell motility. Additionally, 1-palmitoyl LPA enhances the action of beta-lactam antibiotics (ampicillin, piperacillin, and ceftazidime) on various strains of P. aeruginosa, a pathogen associated with pulmonary disease and pneumonia, via binding both Ca2+ and Mg2+.Formal Name: hexadecanoic acid, 2R-hydroxy-3-(phosphonooxy)propyl ester. CAS Number: 7220-34-0. Synonyms: 1-Hexadecanoyl-2-hydroxy-sn-glycero-3-phosphate, 16:0 LPA, LPA 16:0, PA(16:0/0:0), 1-Palmitoyl LPA, 1-Palmitoyl Lysophosphatidic Acid. Molecular Formula: C19H39O7P. Formula Weight: 410.5. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 2 mg/ml, DMSO: 2.5 mg/ml, Ethanol: 25 mg/ml, PBS (pH 7.2): 3 mg/ml. SMILES: CCCCCCCCCCCCCCCC(OC[C@@H](O)COP(O)(O)=O)=O. InChi Code: InChI=1S/C19H39O7P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-19(21)25-16-18(20)17-26-27(22,23)24/h18,20H,2-17H2,1H3,(H2,22,23,24)/t18-/m1/s1. InChi Key: YNDYKPRNFWPPFU-GOSISDBHSA-N. Side Chain Carbon Sum: 16:0.