- Search results for Cay14575
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6 products were found matching "Cay14575"!
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Item number: Cay14575-50
1-EBIO is an activator of Ca2+-sensitive K+ channels (EC50 = 490 µM in T84 human carcinoma cells). This action is sensitive to the neurotoxin charybdotoxin (Ki = 3.5 nM). In mouse colonic epithelia, 1-EBIO also activates cAMP-sensitive K+ channels, a response this is inhibited by 293B. In this type of epithelium,...
Keywords: | 1-Ethylbenzimidazolinone, 1-ethyl-1,3-dihydro-2H-benzimidazol-2-one |
Application: | K+ channel activator |
CAS | 10045-45-1 |
MW: | 162.2 D |
From 43.00€
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Item number: Cay14557-5
PB-22 (Cay-14096) is a synthetic cannabinoid that is structurally analogous to the potent aminoalkylindoles like JWH 018 (Cay-10900). It differs from JWH 018 by having 8-hydroxyquinoline replacing the naphthalene group of JWH 018. PB-22 7-hydroxyisoquinoline isomer is a structural isomer of PB-22. The physiological...
Keywords: | 1-pentyl-1H-indole-3-carboxylic acid, 7-isoquinolinyl ester |
Application: | Analytical reference standard, synthetic cannabinoid analog, PB-22 structural isomer |
CAS | 2365471-61-8 |
MW: | 358.4 D |
From 109.00€
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Item number: Cay14579-5
Purvalanol A is a potent, cell-permeable, and selective inhibitor of cyclin-dependent kinases (CDKs) with IC50 values of 4, 70, 35, 850, and 75 nM for cdc2/cyclin B, Cdk2/cyclin A, Cdk2/cyclin E, Cdk4/cyclin D1 and Cdk5-p35, respectively. Purvalanol A reversibly arrests synchronized cells in the G1 and G2 phase of...
Keywords: | NG 60, (2R)-2-[[6-[(3-chlorophenyl)amino]-9-(1-methylethyl)-9H-purin-2-yl]amino]-3-methyl-1-butanol |
Application: | CDK inhibitor |
CAS | 212844-53-6 |
MW: | 388.9 D |
From 43.00€
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Item number: Cay14570-5
11-deoxy-16,16-dimethyl Prostaglandin E2 (11-deoxy-16,16-dimethyl PGE2) is a stable synthetic analog of PGE2. It is an agonist for both EP2 and EP3 receptors. It is an effective inhibitor of gastric acid secretion and ulcer formation in the rat, with ED50 values of 1 mg/kg and 0.021 mg/kg respectively. It is 900...
Keywords: | 11-deoxy-16,16-dimethyl PGE2, 9-oxo-15R-hydroxy-16,16-dimethyl-prosta-5Z,13E-dien-1-oic acid |
Application: | EP receptor agonist |
CAS | 53658-98-3 |
MW: | 364.5 D |
From 86.00€
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Item number: Cay14571-5
AMPA is the defining agonist for the AMPA subgroup of ionotropic glutamate receptors, which mediate excitatory neurotransmission. Because AMPA does not interfere with binding sites for kainic acid (Cay-78050) or NMDA (Cay-14581), it can be used to distinguish AMPA receptor-specific activity that contributes to a...
Keywords: | alpha-amino-3-hydroxy-5-methyl-4-Isoxazolepropionic Acid, alpha-amino-2,3-dihydro-5-methyl-3-oxo-4-isoxazolepropanoic... |
Application: | AMPA receptor agonist |
MW: | 186.2 D |
From 134.00€
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Item number: Cay14574-25
4-DAMP is a potent antagonist of the muscarinic M3 receptor (pKi = 9.3). It is routinely used to study the regulation and functions of the M3 receptor. 4-DAMP also has a high affinity for the closely-related M5 receptor (pKi = 8.9).Formal Name: 4-[(2,2-diphenylacetyl)oxy]-1,1-dimethyl-piperidinium, monoiodide. CAS...
Keywords: | 4-Diphenylacetoxy-N-methyl-piperidine methiodide, 4-[(2,2-diphenylacetyl)oxy]-1,1-dimethyl-piperidinium, monoiodide |
Application: | Muscarinic M3 receptor antagonist |
CAS | 1952-15-4 |
MW: | 451.3 D |
From 56.00€
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