1-Aminoacetone, Hydrochloride

Aminoacetone is a threonine and glycine catabolite that can be converted to methylglyoxal by amine oxidases. It has been identified as one of several endogenous sources of methylglyoxal found in the plasma of diabetes patients. As a pro-oxidant, 0.10-5 mM aminoacetone can induce cell death in RINm5f pancreatic beta-cells. Aminoacetone is used as a growth substrate for Pseudomonas. Synonyms: 1-Amino-2-propanone Hydrochloride, 2-Oxopropylammonium Chloride, Aminoacetone Hydrochloride, CAS No: 7737-17-9, 298-08-8 (free base), Molecular Formula: C3H8ClNO, Molecular Weight: 109.55, Appearance: Off-white to beige, crystalline solid, Purity: >95%, Solubility: DMSO (Slightly), Methanol (Slightly), Water (Slightly), Atmosphere: Inert gas, Stability: Hydroscopic and moisture sensitive, Method for Determining Identity: Proton NMR Spectroscopic analysis, TLC Conditions: SiO2, Dichloromethane, Methanol: NH4OH, 8ml: 2ml: 5 drops, Visualized with UV and AMCS, Single spot. Rf=0.6, Chloride: ~30%, Storage and Stability: May be stored at RT for short-term only. Long-term storage is recommended at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Hygroscopic and moisture sensitive