- Search results for Cay10006794-250
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7 products were found matching "Cay10006794-250"!
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Item number: Cay10006797-250
Xestospongins and araguspongins are marine natural products first isolated from Pacific basin sponges, and noted to have vasodilatory properties. Inositol phosphates (IP) are important signal transduction messengers acting via IP3 receptors to promote the mobilization of Ca2+ from intracellular stores. Araguspongin...
Keywords: | [1R-(1R*,4aR*,11S*,12aR*,13R*,16aR*,23S*,24aR*)]-eicosahydro-5H,17H-1,23:11,13-diethano-2H,14H-[1,11]dioxacycloeicosino[2,... |
Application: | IP3 receptor antagonist |
CAS | 123000-02-2 |
MW: | 446.7 D |
From 533.00€
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COVID-19 Research
Item number: Cay10007964-25
E-64c is an active metabolite of the protease inhibitor E-64d (Cay-13533). E-64c inhibits the cysteine proteases cathepsin B, cathepsin H, and papain but not the serine proteases trypsin, chymotrypsin, or elastase. It reduces the autocatalytic activity of the foot-and-mouth-disease virus (FMDV) leader protease when...
Keywords: | Loxistatin Acid, NSC 694279,... |
Application: | Cysteine protease inhibitor |
CAS | 76684-89-4 |
MW: | 314.4 D |
From 84.00€
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Item number: Cay10007904-25
2-Arachidonoyl glycerol (2-AG) is an endogenous agonist of the central cannabinoid (CB1) receptor. It is present at relatively high levels in the central nervous system and is the most abundant molecular species of monoacylglycerol found in rat brain. Monoacylglycerol lipase (MAGL) hydrolyzes 2-AG to arachidonic...
Keywords: | 1-S-Arachidonoyl-1-mercapto-2,3-propanediol, 5Z,8Z,11Z,14Z-eicosatetraenyl,1-thio glycerol |
Application: | Bioactive lipid assays |
CAS | 1309664-54-7 |
MW: | 394.6 D |
From 39.00€
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Item number: Cay10006974-50
AM630 binds selectively to cannabinoid 2 (CB2) over CB1 receptors with Ki values of 31.2 and 5,152 nM, respectively. AM630 acts as an inverse agonist at CB2 receptors, attenuating the antinociceptive effects of a number of cannabinoids, and as a weak partial agonist at CB1 receptors. It decreases proliferation and...
Keywords: | 6-Iodopravodoline, [6-iodo-2-methyl-1-[2-(4-morpholinyl)ethyl]-1H-indol-3-yl](4-methoxyphenyl)-methanone |
Application: | CB2 receptor antagonist |
CAS | 164178-33-0 |
MW: | 504.4 D |
From 77.00€
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Item number: Cay10007294-50
Anandamide (AEA) is an endogenous cannabinoid that binds to both central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptors. The biological actions of AEA are terminated by cellular uptake and hydrolysis of the amide bond by the enzyme fatty acid amide hydrolase. Arachidonoyl-N-methyl amide is an analog of...
Keywords: | N-methyl-5Z,8Z,11Z,14Z-eicosatetraenamide |
Application: | Bioactive lipid assays |
CAS | 156910-29-1 |
MW: | 317.5 D |
From 56.00€
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Item number: Cay16794-250
(R)-Ibuprofen is a non-steroidal anti-inflammatory drug (NSAID) and an isomer of (±)-ibuprofen (Cay-70280). Unlike (S)-ibuprofen (Cay-16793), (R)-ibuprofen does not inhibit COX-1 or COX-2 in vitro (IC50s = 360 and 15.6 µM, respectively) but is converted to the active (S)-enantiomer in vivo. It inhibits NF-kappaB...
Keywords: | (-)-Ibuprofen, alpha-methyl-4-(2-methylpropyl)-(alphaR)-benzeneacetic acid |
Application: | NF-kappaB activation inhibitor |
CAS | 51146-57-7 |
MW: | 206.3 D |
From 104.00€
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Item number: Cay10006790-1
ChREBP (carbohydrate response element-binding protein) is a transcription factor playing a critical role in the nutrient and hormonal regulation of genes encoding enzymes of glucose metabolism and lipogenesis pathways. It contains several domains including a nuclear localization signal (NSL) near the N-terminus,...
Keywords: | Carbohydrate Response Element-binding Protein, WBSCR14 |
Application: | Blocking |
177.00€
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