- Search results for Cay11187
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6 products were found matching "Cay11187"!
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Item number: Cay11187-5
The bromodomain and extra terminal domain (BET) family of proteins, including BRD2, BRD3, and BRD4, play a key role in many cellular processes, including inflammatory gene expression, mitosis, and viral/host interaction by controlling the assembly of histone acetylation-dependent chromatin complexes. JQ1 displaces...
Keywords: | (6S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetic acid,... |
Application: | BRD4 inhibitor |
CAS | 1268524-70-4 |
MW: | 457 D |
From 35.00€
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Item number: Cay18877-5
Gardiquimod is an agonist of human toll-like receptor 7 (TLR7), but not human TLR8, although it activates both porcine TLR7 and TLR8. At 0.5 to 2 µg/ml, it enhances the immunosuppressive activity of T regulatory cells. Gardiquimod is effective as a mucosal adjuvant for Norwalk virus-like particles and inhibits...
Keywords: | 4-amino-2-[(ethylamino)methyl]-alpha,alpha-dimethyl-1H-imidazo[4,5-c]quinoline-1-ethanol |
Application: | TLR7 agonist |
CAS | 1020412-43-4 |
MW: | 313.4 D |
From 66.00€
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Item number: Cay11877-5
AB-005 (Cay-11766) is a synthetic cannabinoid (CB) built on a 1-[(1-methylpiperidin-2-yl)methyl]-indole base that is characteristic of a series of potent CBs, including AM1220 (Cay-9001055), AM1241 (Cay-10010118), and AM1248 (Cay-11282). AB-005 azepane isomer is a variant of AB-005 in which the methylpiperidine...
Keywords: | [1-(hexahydro-1-methyl-1H-azepin-3-yl)-1H-indol-3-yl](2,2,3,3-tetramethylcyclopropyl)-methanone |
Application: | Analytical reference standard, Synthetic cannabinoid variant |
CAS | 1445751-74-5 |
MW: | 352.5 D |
From 109.00€
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Item number: Cay11887-5
Protodioscin is a steroidal saponin first isolated from plants used in herbal remedies. It displays cytotoxicity against a range of cancer cells in vitro, including leukemia, colon cancer, and prostate cancer cells (GI50 = 2 µM). Protodioscin, as a part of an extract from the plant T. terrestris, also improves...
Keywords: | NSC 698796, (3beta,22alpha,25R)-26-(beta-D-glucopyranosyloxy)-22-hydroxyfurost-5-en-3-yl... |
Application: | Steroidal saponin, Anticancer |
CAS | 55056-80-9 |
MW: | 1049.2 D |
From 50.00€
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Item number: Cay18777-5
Altiratinib is a multiple kinase inhibitor, blocking Met, Tie2, VEGF2, TrkA, TrkB, and TrkC with IC50 values of 2.7, 8.0, 9.2, 0.85, 4.6, and 0.83 nM, respectively. It also inhibits several mutant Met isoforms at nanomolar concentrations. Altiratinib inhibits the proliferation of several cancer cell lines in vitro...
Keywords: | N-[4-[[2-[(cyclopropylcarbonyl)amino]-4-pyridinyl]oxy]-2,5-difluorophenyl]-N'-(4-fluorophenyl)-1,1-cyclopropanedicarboxamide |
Application: | MET / TIE2 / VEGFR2 inhibitor |
CAS | 1345847-93-9 |
MW: | 510.5 D |
From 43.00€
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Item number: Cay18887-10
Biotin-LC-LC-NHS is a biotinylation reagent that contains an N-hydroxysuccinimide (NHS) moiety, which activates carboxylic acid groups on biotin to facilitate coupling reactions, and a 30.5 Å spacer to decrease steric hindrance. It has been used to biotinylate small molecules such as paclitaxel (Cay-10461) and...
Keywords: | Biotinamidohexanoyl-6-aminohexanoic Acid N-hydroxysuccinimide ester,... |
Application: | Carboxylic acid group biotinylation reagent (NHS) |
CAS | 89889-52-1 |
MW: | 567.7 D |
From 43.00€
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