3 products were found matching "Cay11969"!

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(+)-Etomoxir (sodium salt)
(+)-Etomoxir (sodium salt)

Item number: Cay11969-5

(+)-Etomoxir is an irreversible inhibitor of carnitine palmitoyltransferase 1 (CPT1), an enzyme that combines fatty acyl-CoAs with carnitine for transport into the mitochondria for beta-oxidation. It inhibits fatty acid oxidation in hepatocytes in vitro (IC50s = 0.1, 1, and 10 µM for human, guinea pig, and rat...
Keywords: (R)-(+)-Etomoxir, (2R)-2-[6-(4-chlorophenoxy)hexyl]-2-oxiranecarboxylic acid monosodium salt
Application: Irreversible CPT1 / carnitine O-palmitoyltransferase 1 inhibitor
CAS 828934-41-4
MW: 320.7 D
From 96.00€ *
Review
Birinapant
Birinapant

Item number: Cay19699-5

Birinapant is a bivalent mimetic of the Diablo homolog known as second mitochondria-derived activator of caspase (Smac). It is an antagonist of cellular inhibitor of apoptosis 1 (cIAP1, or BIRC2), cIAP2 (BIRC3), and XIAP (BIRC4), binding each at nanomolar concentrations. Birinapant causes rapid cIAP1 degradation,...
Keywords: TL-32711,...
Application: Antineoplastic, XIAP / cIAP1 inhibitor
CAS 1260251-31-7
MW: 806.9 D
From 77.00€ *
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Anti-PAD4   (Clone 6D8)
Anti-PAD4 (Clone 6D8)

Item number: Cay19669-100

Protein arginine deiminase 4 (PAD4) catalyzes the conversion of arginine residues to citrulline within cellular protein substrates, resulting in the loss of a positive charge, which can alter protein structure and/or function. It is expressed in neutrophils, as well as a variety of tissues, including the brain,...
Keywords: Anti-PAD4, Anti-PADI4, Anti-HL-60 PAD, Anti-HL-60 PAD, Anti-Peptidylarginine deiminase IV, Anti-Peptidylarginine deiminase...
Application: ELISA, WB
Host: Mouse
Species reactivity: human
535.00€ *
Review