(+)-15-epi Cloprostenol

Cloprostenol is a synthetic prostaglandin F2alpha (PGF2alpha) analog and a potent FP receptor agonist. (+)-15-epi Cloprostenol is the 15(S), or 15beta-hydroxy enantiomer of (+)-cloprostenol. This epimer is less active by several orders of magnitude as an FP receptor ligand when compared to 15(R)-cloprostenol. However, the specific activity of this isomer has not been well studied.Formal Name: (+)-9alpha,11alpha,15S-trihydroxy-16-(3-chlorophenoxy)-17,18,19,20-tetranor-prosta-5Z,13E-dien-1-oic acid. CAS Number: 54276-22-1. Synonyms: D-Cloprostenol, (+)-15(S)-Cloprostenol. Molecular Formula: C22H29ClO6. Formula Weight: 424.9. Purity: >98%. Formulation: (Request formulation change), A solution in ethanol. Solubility: DMF: 50 mg/ml, DMSO: 50 mg/ml, Ethanol: 50 mg/ml, PBS (pH 7.2): 1 mg/ml. lambdamax: 204, 275 nm. SMILES: OC(=O)CCC/C=C\CC1C(O)CC(O)[C@@H]1\C=C\[C@H](O)COc1cccc(Cl)c1. InChi Code: InChI=1S/C22H29ClO6/c23-15-6-5-7-17(12-15)29-14-16(24)10-11-19-18(20(25)13-21(19)26)8-3-1-2-4-9-22(27)28/h1,3,5-7,10-12,16,18-21,24-26H,2,4,8-9,13-14H2,(H,27,28)/b3-1-,11-10+/t16-,18+,19+,20-,21+/m0/s1. InChi Key: VJGGHXVGBSZVMZ-HBWANGNJSA-N.